My Bibliography

select

Ahmad S, Wrennall JA, Goriounova AS, Sekhri M, Iskarpatyoti JA, Ghosh A, Abdelwahab SH, Voeller A, Rai M, Mahida RY, Krajewski K, Ignar DM, Greenbaum A, Moran TP, Tilley SL, Thickett DR, Sassano MF, Tarran R. Specific Inhibition of Orai1-mediated Calcium Signalling Resolves Inflammation and Clears Bacteria in an Acute Respiratory Distress Syndrome Model. Am J Respir Crit Care Med. 2024 Mar 15;209(6):703-715. doi: 10.1164/rccm.202308-1393OC. PubMed PMID: 37972349; PubMed Central PMCID: PMC10945054.

select

Schworer SA, Moran TP. Pulmonary Interstitial Macrophages stIMulate Regulatory T Cell Responses. Am J Respir Cell Mol Biol. 2024 Mar 6;. doi: 10.1165/rcmb.2024-0049ED. [Epub ahead of print] PubMed PMID: 38445963.

select

Immormino RM, Smeekens JM, Mathai PI, Clough KM, Nguyen JT, Ghio AJ, Cook DN, Kulis MD, Moran TP. Different airborne particulates trigger distinct immune pathways leading to peanut allergy in a mouse model. Allergy. 2024 Feb;79(2):432-444. doi: 10.1111/all.15908. Epub 2023 Oct 7. PubMed PMID: 37804001; PubMed Central PMCID: PMC11017991.

select

Smeekens JM, Immormino RM, Kesselring JR, Turner AV, Kulis MD, Moran TP. A single priming event prevents oral tolerance to peanut. Clin Exp Allergy. 2023 Sep;53(9):930-940. doi: 10.1111/cea.14373. Epub 2023 Jul 12. PubMed PMID: 37437951; PubMed Central PMCID: PMC10528191.

select

Immormino RM, Smeekens JM, Mathai PI, Kesselring JR, Turner AV, Kulis MD, Moran TP. Peanut butter feeding induces oral tolerance in genetically diverse collaborative cross mice. Front Allergy. 2023;4:1219268. doi: 10.3389/falgy.2023.1219268. eCollection 2023. PubMed PMID: 37528863; PubMed Central PMCID: PMC10387557.

select

Donoghue LJ, McFadden KM, Vargas D, Smith GJ, Immormino RM, Moran TP, Kelada SNP. Collaborative cross strain CC011/UncJ as a novel mouse model of T2-high, severe asthma. Respir Res. 2023 Jun 9;24(1):153. doi: 10.1186/s12931-023-02453-y. PubMed PMID: 37296458; PubMed Central PMCID: PMC10251525.

select

Moran TP. Impact of the exposome on food allergy development. Curr Opin Allergy Clin Immunol. 2023 Apr 1;23(2):164-171. doi: 10.1097/ACI.0000000000000889. Epub 2023 Jan 11. Review. PubMed PMID: 36728313; PubMed Central PMCID: PMC9985871.

select

Hickman E, Smyth T, Cobos-Uribe C, Immormino R, Rebuli ME, Moran T, Alexis NE, Jaspers I. Expanded characterization of in vitro polarized M0, M1, and M2 human monocyte-derived macrophages: Bioenergetic and secreted mediator profiles. PLoS One. 2023;18(3):e0279037. doi: 10.1371/journal.pone.0279037. eCollection 2023. PubMed PMID: 36862675; PubMed Central PMCID: PMC9980743.

select

Moran TP, Kulis MD. A "LEAP" forward in understanding immune mechanisms of oral tolerance to peanut. J Allergy Clin Immunol. 2022 Aug;150(2):299-301. doi: 10.1016/j.jaci.2022.04.022. Epub 2022 Apr 28. PubMed PMID: 35490903; PubMed Central PMCID: PMC9635268.

select

Winslow A, Jalazo ER, Evans A, Winstead M, Moran T. A De Novo Cause of PGM3 Deficiency Treated with Hematopoietic Stem Cell Transplantation. J Clin Immunol. 2022 Apr;42(3):691-694. doi: 10.1007/s10875-021-01196-z. Epub 2022 Jan 18. PubMed PMID: 35040011; PubMed Central PMCID: PMC8763434.

select

Immormino RM, Jania CM, Tilley SL, Moran TP. Neuropilin-2 regulates airway inflammation in a neutrophilic asthma model. Immun Inflamm Dis. 2022 Mar;10(3):e575. doi: 10.1002/iid3.575. Epub 2021 Dec 3. PubMed PMID: 34861108; PubMed Central PMCID: PMC8926497.

select

Tovar A, Crouse WL, Smith GJ, Thomas JM, Keith BP, McFadden KM, Moran TP, Furey TS, Kelada SNP. Integrative analysis reveals mouse strain-dependent responses to acute ozone exposure associated with airway macrophage transcriptional activity. Am J Physiol Lung Cell Mol Physiol. 2022 Jan 1;322(1):L33-L49. doi: 10.1152/ajplung.00237.2021. Epub 2021 Nov 10. PubMed PMID: 34755540; PubMed Central PMCID: PMC8721896.

select

Smith GJ, Tovar A, McFadden K, Moran TP, Wagner JG, Harkema JR, Kelada SNP. A Murine Model of Ozone-induced Nonatopic Asthma from the Collaborative Cross. Am J Respir Cell Mol Biol. 2021 Dec;65(6):672-674. doi: 10.1165/rcmb.2020-0577LE. PubMed PMID: 34851239; PubMed Central PMCID: PMC8641798.

select

Kulis MD, Smeekens JM, Immormino RM, Moran TP. The airway as a route of sensitization to peanut: An update to the dual allergen exposure hypothesis. J Allergy Clin Immunol. 2021 Sep;148(3):689-693. doi: 10.1016/j.jaci.2021.05.035. Epub 2021 Jun 7. Review. PubMed PMID: 34111450; PubMed Central PMCID: PMC8429226.

select

Forster M, Moran T, Beaven A, Voorhees T. Novel ZAP-70-Related Immunodeficiency Presenting with Epstein-Barr Virus Lymphoproliferative Disorder and Hemophagocytic Lymphohistiocytosis. Case Reports Immunol. 2021;2021:6587323. doi: 10.1155/2021/6587323. eCollection 2021. PubMed PMID: 34239742; PubMed Central PMCID: PMC8238617.

select

Smeekens JM, Johnson-Weaver BT, Hinton AL, Azcarate-Peril MA, Moran TP, Immormino RM, Kesselring JR, Steinbach EC, Orgel KA, Staats HF, Burks AW, Mucha PJ, Ferris MT, Kulis MD. Fecal IgA, Antigen Absorption, and Gut Microbiome Composition Are Associated With Food Antigen Sensitization in Genetically Susceptible Mice. Front Immunol. 2020;11:599637. doi: 10.3389/fimmu.2020.599637. eCollection 2020. PubMed PMID: 33542716; PubMed Central PMCID: PMC7850988.

select

Smeekens JM, Immormino RM, Kulis MD, Moran TP. Timing of exposure to environmental adjuvants is critical to mitigate peanut allergy. J Allergy Clin Immunol. 2021 Jan;147(1):387-390.e4. doi: 10.1016/j.jaci.2020.09.011. Epub 2020 Sep 24. PubMed PMID: 32980426; PubMed Central PMCID: PMC7855661.

select

Moran TP. The External Exposome and Food Allergy. Curr Allergy Asthma Rep. 2020 Jun 6;20(8):37. doi: 10.1007/s11882-020-00936-2. Review. PubMed PMID: 32506329; PubMed Central PMCID: PMC8100692.

select

Smeekens JM, Immormino RM, Balogh PA, Randell SH, Kulis MD, Moran TP. Indoor dust acts as an adjuvant to promote sensitization to peanut through the airway. Clin Exp Allergy. 2019 Nov;49(11):1500-1511. doi: 10.1111/cea.13486. Epub 2019 Sep 10. PubMed PMID: 31444814; PubMed Central PMCID: PMC7171466.

select

Lin L, Moran TP, Peng B, Yang J, Culton DA, Che H, Jiang S, Liu Z, Geng S, Zhang Y, Diaz LA, Qian Y. Walnut antigens can trigger autoantibody development in patients with pemphigus vulgaris through a "hit-and-run" mechanism. J Allergy Clin Immunol. 2019 Sep;144(3):720-728.e4. doi: 10.1016/j.jaci.2019.04.020. Epub 2019 May 6. PubMed PMID: 31071340; PubMed Central PMCID: PMC6742533.

select

Immormino RM, Lauzier DC, Nakano H, Hernandez ML, Alexis NE, Ghio AJ, Tilley SL, Doerschuk CM, Peden DB, Cook DN, Moran TP. Neuropilin-2 regulates airway inflammatory responses to inhaled lipopolysaccharide. Am J Physiol Lung Cell Mol Physiol. 2018 Aug 1;315(2):L202-L211. doi: 10.1152/ajplung.00067.2018. Epub 2018 Apr 19. PubMed PMID: 29671604; PubMed Central PMCID: PMC6139664.

select

Dellon ES, Lin L, Beitia R, Moran TP, Qian Y. Serum autoantibodies against epithelial cell adhesion molecules as disease biomarkers of eosinophilic esophagitis. Clin Exp Allergy. 2018 Mar;48(3):343-346. doi: 10.1111/cea.13070. Epub 2017 Dec 12. PubMed PMID: 29193433; PubMed Central PMCID: PMC5828977.

select

Iweala OI, Copenhaver C, Wu EY, Moran TP. Hydroxychloroquine as a steroid-sparing agent in an infant with chronic urticaria. Ann Allergy Asthma Immunol. 2018 Jan;120(1):102-104. doi: 10.1016/j.anai.2017.10.011. Epub 2017 Nov 20. PubMed PMID: 29157861; PubMed Central PMCID: PMC5934996.

select

Whitehead GS, Thomas SY, Shalaby KH, Nakano K, Moran TP, Ward JM, Flake GP, Nakano H, Cook DN. TNF is required for TLR ligand-mediated but not protease-mediated allergic airway inflammation. J Clin Invest. 2017 Sep 1;127(9):3313-3326. doi: 10.1172/JCI90890. Epub 2017 Jul 31. PubMed PMID: 28758900; PubMed Central PMCID: PMC5669552.

select

Moran TP, Nakano K, Whitehead GS, Thomas SY, Cook DN, Nakano H. Inhaled house dust programs pulmonary dendritic cells to promote type 2 T-cell responses by an indirect mechanism. Am J Physiol Lung Cell Mol Physiol. 2015 Nov 15;309(10):L1208-18. doi: 10.1152/ajplung.00256.2015. Epub 2015 Sep 18. PubMed PMID: 26386119; PubMed Central PMCID: PMC4652150.

select

Moran TP, Burks AW. Is clinical tolerance possible after allergen immunotherapy?. Curr Allergy Asthma Rep. 2015 May;15(5):23. doi: 10.1007/s11882-015-0523-3. Review. PubMed PMID: 26139331; PubMed Central PMCID: PMC4766811.

select

Nakano H, Moran TP, Nakano K, Gerrish KE, Bortner CD, Cook DN. Complement receptor C5aR1/CD88 and dipeptidyl peptidase-4/CD26 define distinct hematopoietic lineages of dendritic cells. J Immunol. 2015 Apr 15;194(8):3808-19. doi: 10.4049/jimmunol.1402195. Epub 2015 Mar 13. PubMed PMID: 25769922; PubMed Central PMCID: PMC4390500.

select

Moran TP, Nakano H, Kondilis-Mangum HD, Wade PA, Cook DN. Epigenetic control of Ccr7 expression in distinct lineages of lung dendritic cells. J Immunol. 2014 Nov 15;193(10):4904-13. doi: 10.4049/jimmunol.1401104. Epub 2014 Oct 8. PubMed PMID: 25297875; PubMed Central PMCID: PMC4225164.

select

Moran TP, Vickery BP. The Epithelial Cell-Derived Atopic Dermatitis Cytokine TSLP Activates Neurons to Induce Itch. Pediatrics. 2014 Nov;134 Suppl 3(Suppl 3):S160-1. doi: 10.1542/peds.2014-1817VV. PubMed PMID: 25363954; PubMed Central PMCID: PMC4536588.

select

Lin KL, Fulton LM, Berginski M, West ML, Taylor NA, Moran TP, Coghill JM, Blazar BR, Bear JE, Serody JS. Intravital imaging of donor allogeneic effector and regulatory T cells with host dendritic cells during GVHD. Blood. 2014 Mar 6;123(10):1604-14. doi: 10.1182/blood-2013-09-526020. Epub 2014 Jan 10. PubMed PMID: 24415540; PubMed Central PMCID: PMC3945868.

select

Moran TP, Vickery BP, Burks AW. Oral and sublingual immunotherapy for food allergy: current progress and future directions. Curr Opin Immunol. 2013 Dec;25(6):781-7. doi: 10.1016/j.coi.2013.07.011. Epub 2013 Aug 20. Review. PubMed PMID: 23972904; PubMed Central PMCID: PMC3935613.

select

Coghill JM, Sarantopoulos S, Moran TP, Murphy WJ, Blazar BR, Serody JS. Effector CD4+ T cells, the cytokines they generate, and GVHD: something old and something new. Blood. 2011 Mar 24;117(12):3268-76. doi: 10.1182/blood-2010-12-290403. Epub 2011 Jan 18. Review. PubMed PMID: 21245483; PubMed Central PMCID: PMC3069668.

select

Burgents JE, Moran TP, West ML, Davis NL, Johnston RE, Serody JS. The immunosuppressive tumor environment is the major impediment to successful therapeutic vaccination in Neu transgenic mice. J Immunother. 2010 Jun;33(5):482-91. doi: 10.1097/CJI.0b013e3181d756bb. PubMed PMID: 20463599.

select

Coghill JM, Carlson MJ, Moran TP, Serody JS. The biology and therapeutic potential of natural regulatory T-cells in the bone marrow transplant setting. Leuk Lymphoma. 2008 Oct;49(10):1860-9. doi: 10.1080/10428190802272684. Review. PubMed PMID: 18661393.

select

Ljungberg K, Whitmore AC, Fluet ME, Moran TP, Shabman RS, Collier ML, Kraus AA, Thompson JM, Montefiori DC, Beard C, Johnston RE. Increased immunogenicity of a DNA-launched Venezuelan equine encephalitis virus-based replicon DNA vaccine. J Virol. 2007 Dec;81(24):13412-23. doi: 10.1128/JVI.01799-07. Epub 2007 Oct 3. PubMed PMID: 17913817; PubMed Central PMCID: PMC2168848.

select

Moran TP, Burgents JE, Long B, Ferrer I, Jaffee EM, Tisch RM, Johnston RE, Serody JS. Alphaviral vector-transduced dendritic cells are successful therapeutic vaccines against neu-overexpressing tumors in wild-type mice. Vaccine. 2007 Sep 4;25(36):6604-12. doi: 10.1016/j.vaccine.2007.06.058. Epub 2007 Jul 17. PubMed PMID: 17675184; PubMed Central PMCID: PMC2692294.

select

Moran TP, Collier M, McKinnon KP, Davis NL, Johnston RE, Serody JS. A novel viral system for generating antigen-specific T cells. J Immunol. 2005 Sep 1;175(5):3431-8. doi: 10.4049/jimmunol.175.5.3431. PubMed PMID: 16116238.

select

Poluektova L, Moran T, Zelivyanskaya M, Swindells S, Gendelman HE, Persidsky Y. The regulation of alpha chemokines during HIV-1 infection and leukocyte activation: relevance for HIV-1-associated dementia. J Neuroimmunol. 2001 Nov 1;120(1-2):112-28. doi: 10.1016/s0165-5728(01)00413-1. PubMed PMID: 11694326.

select

A single priming event prevents oral tolerance to peanut. Clinical and experimental allergy : journal of the British Society for Allergy and Clinical Immunology. . NIHMSID: NIHMS1921366.