My Bibliography

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McParland ED, Butcher TA, Gurley NJ, Johnson RI, Slep KC, Peifer M. The Dilute domain in Canoe is not essential for linking cell junctions to the cytoskeleton but supports morphogenesis robustness. J Cell Sci. 2024 Mar 15;137(6). doi: 10.1242/jcs.261734. Epub 2024 Mar 21. PubMed PMID: 38323935; PubMed Central PMCID: PMC11006394.

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Gurley NJ, Szymanski RA, Dowen RH, Butcher TA, Ishiyama N, Peifer M. Exploring the evolution and function of Canoe's intrinsically disordered region in linking cell-cell junctions to the cytoskeleton during embryonic morphogenesis. PLoS One. 2023;18(8):e0289224. doi: 10.1371/journal.pone.0289224. eCollection 2023. PubMed PMID: 37535684; PubMed Central PMCID: PMC10399776.

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Schmidt A, Finegan T, Häring M, Kong D, Fletcher AG, Alam Z, Grosshans J, Wolf F, Peifer M. Polychaetoid/ZO-1 strengthens cell junctions under tension while localizing differently than core adherens junction proteins. Mol Biol Cell. 2023 Jul 1;34(8):ar81. doi: 10.1091/mbc.E23-03-0077. Epub 2023 May 10. PubMed PMID: 37163320; PubMed Central PMCID: PMC10398881.

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Gurley NJ, Szymanski RA, Dowen RH, Butcher TA, Ishiyama N, Peifer M. Exploring the evolution and function of Canoeâ€™s intrinsically disordered region in linking cell-cell junctions to the cytoskeleton during embryonic morphogenesis. bioRxiv. 2023 Mar 6;. doi: 10.1101/2023.03.06.531372. PubMed PMID: 36945496; PubMed Central PMCID: PMC10028902.

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Perez-Vale KZ, Yow KD, Gurley NJ, Greene M, Peifer M. Rap1 regulates apical contractility to allow embryonic morphogenesis without tissue disruption and acts in part via Canoe-independent mechanisms. Mol Biol Cell. 2023 Jan 1;34(1):ar7. doi: 10.1091/mbc.E22-05-0176. Epub 2022 Oct 26. PubMed PMID: 36287827; PubMed Central PMCID: PMC9816648.

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Fernandez-Gonzalez R, Peifer M. Powering morphogenesis: multiscale challenges at the interface of cell adhesion and the cytoskeleton. Mol Biol Cell. 2022 Jul 1;33(8). doi: 10.1091/mbc.E21-09-0452. Review. PubMed PMID: 35696393; PubMed Central PMCID: PMC9635287.

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Yu-Kemp HC, Szymanski RA, Cortes DB, Gadda NC, Lillich ML, Maddox AS, Peifer M. Micron-scale supramolecular myosin arrays help mediate cytoskeletal assembly at mature adherens junctions. J Cell Biol. 2022 Jan 3;221(1). doi: 10.1083/jcb.202103074. Epub 2021 Nov 23. PubMed PMID: 34812842; PubMed Central PMCID: PMC8614156.

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Perez-Vale KZ, Yow KD, Johnson RI, Byrnes AE, Finegan TM, Slep KC, Peifer M. Multivalent interactions make adherens junction-cytoskeletal linkage robust during morphogenesis. J Cell Biol. 2021 Dec 6;220(12). doi: 10.1083/jcb.202104087. Epub 2021 Nov 11. PubMed PMID: 34762121; PubMed Central PMCID: PMC8590279.

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Peifer M. Looking back on a life of unacknowledged privilege and a call to action. Mol Biol Cell. 2021 May 15;32(11):1081-1085. doi: 10.1091/mbc.E21-01-0024. PubMed PMID: 33983852; PubMed Central PMCID: PMC8351539.

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Rogers EM, Allred SC, Peifer M. Abelson kinase's intrinsically disordered region plays essential roles in protein function and protein stability. Cell Commun Signal. 2021 Feb 24;19(1):27. doi: 10.1186/s12964-020-00703-w. PubMed PMID: 33627133; PubMed Central PMCID: PMC7905622.

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Perez-Vale KZ, Peifer M. Orchestrating morphogenesis: building the body plan by cell shape changes and movements. Development. 2020 Sep 11;147(17). doi: 10.1242/dev.191049. Review. PubMed PMID: 32917667; PubMed Central PMCID: PMC7502592.

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Schmidt A, Peifer M. Scribble and Dlg organize a protection racket to ensure apical-basal polarity. Proc Natl Acad Sci U S A. 2020 Jun 16;117(24):13188-13190. doi: 10.1073/pnas.2007739117. Epub 2020 May 29. PubMed PMID: 32471949; PubMed Central PMCID: PMC7306729.

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Schaefer KN, Pronobis MI, Williams CE, Zhang S, Bauer L, Goldfarb D, Yan F, Major MB, Peifer M. Wnt regulation: exploring Axin-Disheveled interactions and defining mechanisms by which the SCF E3 ubiquitin ligase is recruited to the destruction complex. Mol Biol Cell. 2020 May 1;31(10):992-1014. doi: 10.1091/mbc.E19-11-0647. Epub 2020 Mar 4. PubMed PMID: 32129710; PubMed Central PMCID: PMC7346726.

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Peifer M. The Eighth Day of Creation: looking back across 40 years to the birth of molecular biology and the roots of modern cell biology. Mol Biol Cell. 2020 Jan 15;31(2):81-86. doi: 10.1091/mbc.E19-11-0619. PubMed PMID: 31935171; PubMed Central PMCID: PMC6960408.

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Bonello TT, Choi W, Peifer M. Scribble and Discs-large direct initial assembly and positioning of adherens junctions during the establishment of apical-basal polarity. Development. 2019 Nov 21;146(22). doi: 10.1242/dev.180976. PubMed PMID: 31628110; PubMed Central PMCID: PMC6899021.

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Spracklen AJ, Thornton-Kolbe EM, Bonner AN, Florea A, Compton PJ, Fernandez-Gonzalez R, Peifer M. The Crk adapter protein is essential for Drosophila embryogenesis, where it regulates multiple actin-dependent morphogenic events. Mol Biol Cell. 2019 Aug 15;30(18):2399-2421. doi: 10.1091/mbc.E19-05-0302. Epub 2019 Jul 18. PubMed PMID: 31318326; PubMed Central PMCID: PMC6741062.

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Manning LA, Perez-Vale KZ, Schaefer KN, Sewell MT, Peifer M. The Drosophila Afadin and ZO-1 homologues Canoe and Polychaetoid act in parallel to maintain epithelial integrity when challenged by adherens junction remodeling. Mol Biol Cell. 2019 Jul 22;30(16):1938-1960. doi: 10.1091/mbc.E19-04-0209. Epub 2019 Jun 12. PubMed PMID: 31188739; PubMed Central PMCID: PMC6727765.

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Poulton JS, McKay DJ, Peifer M. Centrosome Loss Triggers a Transcriptional Program To Counter Apoptosis-Induced Oxidative Stress. Genetics. 2019 May;212(1):187-211. doi: 10.1534/genetics.119.302051. Epub 2019 Mar 13. PubMed PMID: 30867197; PubMed Central PMCID: PMC6499520.

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Bonello TT, Peifer M. Scribble: A master scaffold in polarity, adhesion, synaptogenesis, and proliferation. J Cell Biol. 2019 Mar 4;218(3):742-756. doi: 10.1083/jcb.201810103. Epub 2018 Dec 31. Review. PubMed PMID: 30598480; PubMed Central PMCID: PMC6400555.

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Schaefer KN, Peifer M. Wnt/Beta-Catenin Signaling Regulation and a Role for Biomolecular Condensates. Dev Cell. 2019 Feb 25;48(4):429-444. doi: 10.1016/j.devcel.2019.01.025. Review. PubMed PMID: 30782412; PubMed Central PMCID: PMC6386181.

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Perez-Vale KZ, Peifer M. Modulating apical-basal polarity by building and deconstructing a Yurt. J Cell Biol. 2018 Nov 5;217(11):3772-3773. doi: 10.1083/jcb.201810059. Epub 2018 Oct 25. PubMed PMID: 30361467; PubMed Central PMCID: PMC6219707.

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Fadero TC, Gerbich TM, Rana K, Suzuki A, DiSalvo M, Schaefer KN, Heppert JK, Boothby TC, Goldstein B, Peifer M, Allbritton NL, Gladfelter AS, Maddox AS, Maddox PS. LITE microscopy: Tilted light-sheet excitation of model organisms offers high resolution and low photobleaching. J Cell Biol. 2018 May 7;217(5):1869-1882. doi: 10.1083/jcb.201710087. Epub 2018 Feb 28. PubMed PMID: 29490939; PubMed Central PMCID: PMC5940309.

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Schaefer KN, Bonello TT, Zhang S, Williams CE, Roberts DM, McKay DJ, Peifer M. Supramolecular assembly of the beta-catenin destruction complex and the effect of Wnt signaling on its localization, molecular size, and activity in vivo. PLoS Genet. 2018 Apr;14(4):e1007339. doi: 10.1371/journal.pgen.1007339. eCollection 2018 Apr. PubMed PMID: 29641560; PubMed Central PMCID: PMC5912785.

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Bonello TT, Perez-Vale KZ, Sumigray KD, Peifer M. Rap1 acts via multiple mechanisms to position Canoe and adherens junctions and mediate apical-basal polarity establishment. Development. 2018 Jan 26;145(2). doi: 10.1242/dev.157941. PubMed PMID: 29361565; PubMed Central PMCID: PMC5825837.

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Peifer M. The argument for diversifying the NIH grant portfolio. Mol Biol Cell. 2017 Nov 1;28(22):2935-2940. doi: 10.1091/mbc.E17-07-0462. PubMed PMID: 29084912; PubMed Central PMCID: PMC5662253.

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Gladfelter AS, Peifer M. What your PI forgot to tell you: why you actually might want a job running a research lab. Mol Biol Cell. 2017 Jul 1;28(13):1724-1727. doi: 10.1091/mbc.E17-02-0091. PubMed PMID: 28663288; PubMed Central PMCID: PMC5491180.

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Poulton JS, Cuningham JC, Peifer M. Centrosome and spindle assembly checkpoint loss leads to neural apoptosis and reduced brain size. J Cell Biol. 2017 May 1;216(5):1255-1265. doi: 10.1083/jcb.201607022. Epub 2017 Mar 28. PubMed PMID: 28351851; PubMed Central PMCID: PMC5412557.

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Pronobis MI, Deuitch N, Posham V, Mimori-Kiyosue Y, Peifer M. Reconstituting regulation of the canonical Wnt pathway by engineering a minimal β-catenin destruction machine. Mol Biol Cell. 2017 Jan 1;28(1):41-53. doi: 10.1091/mbc.E16-07-0557. Epub 2016 Nov 16. PubMed PMID: 27852897; PubMed Central PMCID: PMC5221518.

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Rogers EM, Spracklen AJ, Bilancia CG, Sumigray KD, Allred SC, Nowotarski SH, Schaefer KN, Ritchie BJ, Peifer M. Abelson kinase acts as a robust, multifunctional scaffold in regulating embryonic morphogenesis. Mol Biol Cell. 2016 Aug 15;27(16):2613-31. doi: 10.1091/mbc.E16-05-0292. Epub 2016 Jul 6. PubMed PMID: 27385341; PubMed Central PMCID: PMC4985262.

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Pronobis MI, Deuitch N, Peifer M. The Miraprep: A Protocol that Uses a Miniprep Kit and Provides Maxiprep Yields. PLoS One. 2016;11(8):e0160509. doi: 10.1371/journal.pone.0160509. eCollection 2016. PubMed PMID: 27486871; PubMed Central PMCID: PMC4972323.

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Choi W, Acharya BR, Peyret G, Fardin MA, Mège RM, Ladoux B, Yap AS, Fanning AS, Peifer M. Remodeling the zonula adherens in response to tension and the role of afadin in this response. J Cell Biol. 2016 Apr 25;213(2):243-60. doi: 10.1083/jcb.201506115. PubMed PMID: 27114502; PubMed Central PMCID: PMC5084271.

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Lerit DA, Poulton JS. Centrosomes are multifunctional regulators of genome stability. Chromosome Res. 2016 Jan;24(1):5-17. doi: 10.1007/s10577-015-9506-4. Review. PubMed PMID: 26658800; PubMed Central PMCID: PMC4726469.

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Spracklen AJ, Peifer M. Actin and Apical Constriction: Some (Re)-Assembly Required. Dev Cell. 2015 Dec 21;35(6):662-4. doi: 10.1016/j.devcel.2015.12.006. PubMed PMID: 26702822.

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Pronobis MI, Rusan NM, Peifer M. A novel GSK3-regulated APC:Axin interaction regulates Wnt signaling by driving a catalytic cycle of efficient βcatenin destruction. Elife. 2015 Sep 22;4:e08022. doi: 10.7554/eLife.08022. PubMed PMID: 26393419; PubMed Central PMCID: PMC4568445.

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Lerit DA, Jordan HA, Poulton JS, Fagerstrom CJ, Galletta BJ, Peifer M, Rusan NM. Interphase centrosome organization by the PLP-Cnn scaffold is required for centrosome function. J Cell Biol. 2015 Jul 6;210(1):79-97. doi: 10.1083/jcb.201503117. PubMed PMID: 26150390; PubMed Central PMCID: PMC4494003.

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Terzo EA, Lyons SM, Poulton JS, Temple BR, Marzluff WF, Duronio RJ. Distinct self-interaction domains promote Multi Sex Combs accumulation in and formation of the Drosophila histone locus body. Mol Biol Cell. 2015 Apr 15;26(8):1559-74. doi: 10.1091/mbc.E14-10-1445. Epub 2015 Feb 18. PubMed PMID: 25694448; PubMed Central PMCID: PMC4395134.

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Nowotarski SH, McKeon N, Moser RJ, Peifer M. The actin regulators Enabled and Diaphanous direct distinct protrusive behaviors in different tissues during Drosophila development. Mol Biol Cell. 2014 Oct 15;25(20):3147-65. doi: 10.1091/mbc.E14-05-0951. Epub 2014 Aug 20. PubMed PMID: 25143400; PubMed Central PMCID: PMC4196866.

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Kannan R, Kuzina I, Wincovitch S, Nowotarski SH, Giniger E. The Abl/enabled signaling pathway regulates Golgi architecture in Drosophila photoreceptor neurons. Mol Biol Cell. 2014 Oct 1;25(19):2993-3005. doi: 10.1091/mbc.E14-02-0729. Epub 2014 Aug 7. PubMed PMID: 25103244; PubMed Central PMCID: PMC4230588.

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Poulton JS, Cuningham JC, Peifer M. Acentrosomal Drosophila epithelial cells exhibit abnormal cell division, leading to cell death and compensatory proliferation. Dev Cell. 2014 Sep 29;30(6):731-45. doi: 10.1016/j.devcel.2014.08.007. Epub 2014 Sep 18. PubMed PMID: 25241934; PubMed Central PMCID: PMC4182331.

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Winkelman JD, Bilancia CG, Peifer M, Kovar DR. Ena/VASP Enabled is a highly processive actin polymerase tailored to self-assemble parallel-bundled F-actin networks with Fascin. Proc Natl Acad Sci U S A. 2014 Mar 18;111(11):4121-6. doi: 10.1073/pnas.1322093111. Epub 2014 Mar 3. PubMed PMID: 24591594; PubMed Central PMCID: PMC3964058.

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Bilancia CG, Winkelman JD, Tsygankov D, Nowotarski SH, Sees JA, Comber K, Evans I, Lakhani V, Wood W, Elston TC, Kovar DR, Peifer M. Enabled negatively regulates diaphanous-driven actin dynamics in vitro and in vivo. Dev Cell. 2014 Feb 24;28(4):394-408. doi: 10.1016/j.devcel.2014.01.015. PubMed PMID: 24576424; PubMed Central PMCID: PMC3992947.

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Tsygankov D, Bilancia CG, Vitriol EA, Hahn KM, Peifer M, Elston TC. CellGeo: a computational platform for the analysis of shape changes in cells with complex geometries. J Cell Biol. 2014 Feb 3;204(3):443-60. doi: 10.1083/jcb.201306067. PubMed PMID: 24493591; PubMed Central PMCID: PMC3912527.

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Manning AJ, Peters KA, Peifer M, Rogers SL. Regulation of epithelial morphogenesis by the G protein-coupled receptor mist and its ligand fog. Sci Signal. 2013 Nov 12;6(301):ra98. doi: 10.1126/scisignal.2004427. PubMed PMID: 24222713; PubMed Central PMCID: PMC4154316.

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Poulton JS, Mu FW, Roberts DM, Peifer M. APC2 and Axin promote mitotic fidelity by facilitating centrosome separation and cytoskeletal regulation. Development. 2013 Oct;140(20):4226-36. doi: 10.1242/dev.094425. Epub 2013 Sep 11. PubMed PMID: 24026117; PubMed Central PMCID: PMC3787761.

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Ellis SJ, Goult BT, Fairchild MJ, Harris NJ, Long J, Lobo P, Czerniecki S, Van Petegem F, Schöck F, Peifer M, Tanentzapf G. Talin autoinhibition is required for morphogenesis. Curr Biol. 2013 Sep 23;23(18):1825-33. doi: 10.1016/j.cub.2013.07.054. Epub 2013 Sep 5. PubMed PMID: 24012314; PubMed Central PMCID: PMC3882074.

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Choi W, Harris NJ, Sumigray KD, Peifer M. Rap1 and Canoe/afadin are essential for establishment of apical-basal polarity in the Drosophila embryo. Mol Biol Cell. 2013 Apr;24(7):945-63. doi: 10.1091/mbc.E12-10-0736. Epub 2013 Jan 30. PubMed PMID: 23363604; PubMed Central PMCID: PMC3608504.

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Gao L, Shao L, Higgins CD, Poulton JS, Peifer M, Davidson MW, Wu X, Goldstein B, Betzig E. Noninvasive imaging beyond the diffraction limit of 3D dynamics in thickly fluorescent specimens. Cell. 2012 Dec 7;151(6):1370-85. doi: 10.1016/j.cell.2012.10.008. PubMed PMID: 23217717; PubMed Central PMCID: PMC3615549.

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Roberts DM, Pronobis MI, Poulton JS, Kane EG, Peifer M. Regulation of Wnt signaling by the tumor suppressor adenomatous polyposis coli does not require the ability to enter the nucleus or a particular cytoplasmic localization. Mol Biol Cell. 2012 Jun;23(11):2041-56. doi: 10.1091/mbc.E11-11-0965. Epub 2012 Apr 18. PubMed PMID: 22513088; PubMed Central PMCID: PMC3364170.

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Sumigray KD, Peifer M. Cell shape by coercion: Par1 and aPKC put the squeeze on junctions. Dev Cell. 2012 May 15;22(5):907-8. doi: 10.1016/j.devcel.2012.04.016. PubMed PMID: 22595665.

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Pronobis MI, Peifer M. Wnt signaling: the many interfaces of β-catenin. Curr Biol. 2012 Feb 21;22(4):R137-9. doi: 10.1016/j.cub.2012.01.002. PubMed PMID: 22361154.