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McMahan RH, Anton P, Coleman LG, Cresci GAM, Crews FT, Crotty KM, Luck ME, Molina PE, Vachharajani V, Weinberg J, Yeligar SM, Choudhry MA, McCullough RL, Kovacs EJ. Alcohol and Immunology: Mechanisms of multi-organ damage. Summary of the 2022 alcohol and Immunology research interest group (AIRIG) meeting. Alcohol. 2023 Aug;110:57-63. doi: 10.1016/j.alcohol.2023.04.002. Epub 2023 Apr 13. Review. PubMed PMID: 37061143; PubMed Central PMCID: PMC10330898.
Li YD, Luo YJ, Xie L, Tart DS, Sheehy RN, Zhang L, Coleman LG Jr, Chen X, Song J. Activation of hypothalamic-enhanced adult-born neurons restores cognitive and affective function in Alzheimer's disease. Cell Stem Cell. 2023 Apr 6;30(4):415-432.e6. doi: 10.1016/j.stem.2023.02.006. PubMed PMID: 37028406; PubMed Central PMCID: PMC10150940.
Crews FT, Coleman LG Jr, Macht VA, Vetreno RP. Targeting Persistent Changes in Neuroimmune and Epigenetic Signaling in Adolescent Drinking to Treat Alcohol Use Disorder in Adulthood. Pharmacol Rev. 2023 Mar;75(2):380-396. doi: 10.1124/pharmrev.122.000710. Epub 2022 Dec 12. Review. PubMed PMID: 36781218; PubMed Central PMCID: PMC9969522.
Seim RF, Willis ML, Wallet SM, Maile R, Coleman LG Jr. EXTRACELLULAR VESICLES AS REGULATORS OF IMMUNE FUNCTION IN TRAUMATIC INJURIES AND SEPSIS. Shock. 2023 Feb 1;59(2):180-189. doi: 10.1097/SHK.0000000000002023. Epub 2022 Dec 16. Review. PubMed PMID: 36516458; PubMed Central PMCID: PMC9940835.
Crotty K, Anton P, Coleman LG, Morris NL, Lewis SA, Samuelson DR, McMahan RH, Hartmann P, Kim A, Ratna A, Mandrekar P, Wyatt TA, Choudhry MA, Kovacs EJ, McCullough R, Yeligar SM. A critical review of recent knowledge of alcohol's effects on the immunological response in different tissues. Alcohol Clin Exp Res (Hoboken). 2023 Jan;47(1):36-44. doi: 10.1111/acer.14979. Epub 2022 Nov 29. Review. PubMed PMID: 36446606; PubMed Central PMCID: PMC9974783.
Zou J, Walter TJ, Barnett A, Rohlman A, Crews FT, Coleman LG Jr. Ethanol Induces Secretion of Proinflammatory Extracellular Vesicles That Inhibit Adult Hippocampal Neurogenesis Through G9a/GLP-Epigenetic Signaling. Front Immunol. 2022;13:866073. doi: 10.3389/fimmu.2022.866073. eCollection 2022. PubMed PMID: 35634322; PubMed Central PMCID: PMC9136051.
Tucker AE, Alicea Pauneto CDM, Barnett AM, Coleman LG Jr. Chronic Ethanol Causes Persistent Increases in Alzheimer's Tau Pathology in Female 3xTg-AD Mice: A Potential Role for Lysosomal Impairment. Front Behav Neurosci. 2022;16:886634. doi: 10.3389/fnbeh.2022.886634. eCollection 2022. PubMed PMID: 35645744; PubMed Central PMCID: PMC9131098.
Coleman LG. The emerging world of subcellular biological medicine: extracellular vesicles as novel biomarkers, targets, and therapeutics. Neural Regen Res. 2022 May;17(5):1020-1022. doi: 10.4103/1673-5374.324846. PubMed PMID: 34558528; PubMed Central PMCID: PMC8552855.
Barnett A, David E, Rohlman A, Nikolova VD, Moy SS, Vetreno RP, Coleman LG Jr. Adolescent Binge Alcohol Enhances Early Alzheimer's Disease Pathology in Adulthood Through Proinflammatory Neuroimmune Activation. Front Pharmacol. 2022;13:884170. doi: 10.3389/fphar.2022.884170. eCollection 2022. PubMed PMID: 35559229; PubMed Central PMCID: PMC9086457.
Willis ML, Mahung C, Wallet SM, Barnett A, Cairns BA, Coleman LG Jr, Maile R. Plasma extracellular vesicles released after severe burn injury modulate macrophage phenotype and function. J Leukoc Biol. 2022 Jan;111(1):33-49. doi: 10.1002/JLB.3MIA0321-150RR. Epub 2021 Aug 3. PubMed PMID: 34342045; PubMed Central PMCID: PMC8716518.
Desai CS, Khan A, Bellio MA, Willis ML, Mahung C, Ma X, Baldwin X, Williams BM, Baron TH, Coleman LG, Wallet SM, Maile R. Characterization of extracellular vesicle miRNA identified in peripheral blood of chronic pancreatitis patients. Mol Cell Biochem. 2021 Dec;476(12):4331-4341. doi: 10.1007/s11010-021-04248-5. Epub 2021 Aug 27. PubMed PMID: 34448998; NIHMSID:NIHMS1756307.
Coleman LG Jr, Crews FT, Vetreno RP. The persistent impact of adolescent binge alcohol on adult brain structural, cellular, and behavioral pathology: A role for the neuroimmune system and epigenetics. Int Rev Neurobiol. 2021;160:1-44. doi: 10.1016/bs.irn.2021.08.001. Epub 2021 Oct 4. Review. PubMed PMID: 34696871.
Maile R, Willis ML, Herring LE, Prevatte A, Mahung C, Cairns B, Wallet S, Coleman LG Jr. Burn Injury Induces Proinflammatory Plasma Extracellular Vesicles That Associate with Length of Hospital Stay in Women: CRP and SAA1 as Potential Prognostic Indicators. Int J Mol Sci. 2021 Sep 18;22(18). doi: 10.3390/ijms221810083. PubMed PMID: 34576246; PubMed Central PMCID: PMC8468249.
Vetreno RP, Qin L, Coleman LG Jr, Crews FT. Increased Toll-like Receptor-MyD88-NFκB-Proinflammatory neuroimmune signaling in the orbitofrontal cortex of humans with alcohol use disorder. Alcohol Clin Exp Res. 2021 Sep;45(9):1747-1761. doi: 10.1111/acer.14669. Epub 2021 Aug 20. PubMed PMID: 34415075; PubMed Central PMCID: PMC8526379.
Crews FT, Zou J, Coleman LG Jr. Extracellular microvesicles promote microglia-mediated pro-inflammatory responses to ethanol. J Neurosci Res. 2021 Aug;99(8):1940-1956. doi: 10.1002/jnr.24813. Epub 2021 Feb 20. PubMed PMID: 33611821; PubMed Central PMCID: PMC8451840.
Barnett AM, Crews FT, Coleman LG. Microglial depletion and repopulation: a new era of regenerative medicine?. Neural Regen Res. 2021 Jun;16(6):1204-1205. doi: 10.4103/1673-5374.300439. PubMed PMID: 33269777; PubMed Central PMCID: PMC8224128.
Qin L, Zou J, Barnett A, Vetreno RP, Crews FT, Coleman LG Jr. TRAIL Mediates Neuronal Death in AUD: A Link between Neuroinflammation and Neurodegeneration. Int J Mol Sci. 2021 Mar 4;22(5). doi: 10.3390/ijms22052547. PubMed PMID: 33806288; PubMed Central PMCID: PMC7961445.
McMahan RH, Afshar M, Amedee AM, Bishehsari F, Carr RM, Coleman LG, Herrnreiter CJ, Lewis SL, Mandrekar P, McCullough RL, Morris NL, Vasiliou V, Wang HJ, Yeligar SM, Choudhry MA, Kovacs EJ. Summary of the 2019 alcohol and immunology research interest group (AIRIG) meeting: Alcohol-mediated mechanisms of multiple organ injury. Alcohol. 2020 Sep;87:89-95. doi: 10.1016/j.alcohol.2020.04.008. Epub 2020 Apr 28. Review. PubMed PMID: 32353591; PubMed Central PMCID: PMC7483664.
Coleman LG Jr, Zou J, Crews FT. Microglial depletion and repopulation in brain slice culture normalizes sensitized proinflammatory signaling. J Neuroinflammation. 2020 Jan 18;17(1):27. doi: 10.1186/s12974-019-1678-y. PubMed PMID: 31954398; PubMed Central PMCID: PMC6969463.
Lawrimore CJ, Coleman LG, Crews FT. Ethanol induces interferon expression in neurons via TRAIL: role of astrocyte-to-neuron signaling. Psychopharmacology (Berl). 2019 Oct;236(10):2881-2897. doi: 10.1007/s00213-018-5153-8. Epub 2019 Jan 4. PubMed PMID: 30610351; PubMed Central PMCID: PMC6646093.
Lawrimore CJ, Coleman LG, Zou J, Crews FT. Ethanol Induction of Innate Immune Signals Across BV2 Microglia and SH-SY5Y Neuroblastoma Involves Induction of IL-4 and IL-13. Brain Sci. 2019 Sep 10;9(9). doi: 10.3390/brainsci9090228. PubMed PMID: 31510019; PubMed Central PMCID: PMC6770440.
Coleman LG Jr, Zou J, Qin L, Crews FT. HMGB1/IL-1β complexes regulate neuroimmune responses in alcoholism. Brain Behav Immun. 2018 Aug;72:61-77. doi: 10.1016/j.bbi.2017.10.027. Epub 2017 Nov 2. PubMed PMID: 29102800; PubMed Central PMCID: PMC5932292.
Coleman LG Jr, Maile R, Jones SW, Cairns BA, Crews FT. HMGB1/IL-1β complexes in plasma microvesicles modulate immune responses to burn injury. PLoS One. 2018;13(3):e0195335. doi: 10.1371/journal.pone.0195335. eCollection 2018. PubMed PMID: 29601597; PubMed Central PMCID: PMC5877880.
Coleman LG Jr, Crews FT. Innate Immune Signaling and Alcohol Use Disorders. Handb Exp Pharmacol. 2018;248:369-396. doi: 10.1007/164_2018_92. PubMed PMID: 29500721; PubMed Central PMCID: PMC6120815.
Crews FT, Lawrimore CJ, Walter TJ, Coleman LG Jr. The role of neuroimmune signaling in alcoholism. Neuropharmacology. 2017 Aug 1;122:56-73. doi: 10.1016/j.neuropharm.2017.01.031. Epub 2017 Feb 1. Review. PubMed PMID: 28159648; PubMed Central PMCID: PMC5493978.
Crews FT, Walter TJ, Coleman LG Jr, Vetreno RP. Toll-like receptor signaling and stages of addiction. Psychopharmacology (Berl). 2017 May;234(9-10):1483-1498. doi: 10.1007/s00213-017-4560-6. Epub 2017 Feb 17. Review. PubMed PMID: 28210782; PubMed Central PMCID: PMC5420377.
Coleman LG Jr, Zou J, Crews FT. Microglial-derived miRNA let-7 and HMGB1 contribute to ethanol-induced neurotoxicity via TLR7. J Neuroinflammation. 2017 Jan 25;14(1):22. doi: 10.1186/s12974-017-0799-4. PubMed PMID: 28118842; PubMed Central PMCID: PMC5264311.
Coleman LG Jr, Liu W, Oguz I, Styner M, Crews FT. Adolescent binge ethanol treatment alters adult brain regional volumes, cortical extracellular matrix protein and behavioral flexibility. Pharmacol Biochem Behav. 2014 Jan;116:142-51. doi: 10.1016/j.pbb.2013.11.021. Epub 2013 Nov 23. PubMed PMID: 24275185; PubMed Central PMCID: PMC3913047.
Coleman LG Jr, Oguz I, Lee J, Styner M, Crews FT. Postnatal day 7 ethanol treatment causes persistent reductions in adult mouse brain volume and cortical neurons with sex specific effects on neurogenesis. Alcohol. 2012 Sep;46(6):603-12. doi: 10.1016/j.alcohol.2012.01.003. Epub 2012 May 7. PubMed PMID: 22572057; PubMed Central PMCID: PMC3552379.
Coleman LG Jr, He J, Lee J, Styner M, Crews FT. Adolescent binge drinking alters adult brain neurotransmitter gene expression, behavior, brain regional volumes, and neurochemistry in mice. Alcohol Clin Exp Res. 2011 Apr;35(4):671-88. doi: 10.1111/j.1530-0277.2010.01385.x. Epub 2011 Jan 11. PubMed PMID: 21223304; PubMed Central PMCID: PMC3544413.
Coleman LG Jr, Jarskog LF, Moy SS, Crews FT. Deficits in adult prefrontal cortex neurons and behavior following early post-natal NMDA antagonist treatment. Pharmacol Biochem Behav. 2009 Sep;93(3):322-30. doi: 10.1016/j.pbb.2009.04.017. Epub 2009 May 3. PubMed PMID: 19409920; PubMed Central PMCID: PMC2798004.
Coleman LG Jr, Polanowska-Grabowska RK, Marcinkiewicz M, Gear AR. LDL oxidized by hypochlorous acid causes irreversible platelet aggregation when combined with low levels of ADP, thrombin, epinephrine, or macrophage-derived chemokine (CCL22). Blood. 2004 Jul 15;104(2):380-9. doi: 10.1182/blood-2003-08-2961. Epub 2004 Mar 30. PubMed PMID: 15054038.
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