My Bibliography

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McCullough MJ, Bose PG, Mock JR. Regulatory T cells: Supporting lung homeostasis and promoting resolution and repair after lung injury. Int J Biochem Cell Biol. 2024 May;170:106568. doi: 10.1016/j.biocel.2024.106568. Epub 2024 Mar 20. Review. PubMed PMID: 38518980; PubMed Central PMCID: PMC11031275.

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McCullough MJ, Tune MK, Cabrera JC, Torres-Castillo J, He M, Feng Y, Doerschuk CM, Dang H, Beltran AS, Hagan RS, Mock JR. Characterization of the MT-2 Treg-like cell line in the presence and absence of forkhead box P3 (FOXP3). Immunol Cell Biol. 2024 Mar;102(3):211-224. doi: 10.1111/imcb.12725. Epub 2024 Jan 30. PubMed PMID: 38288547.

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Leist SR, Mock JR. The Importance of "Negative" Results: Lipid Lessons in Coronavirus Biology. Am J Respir Cell Mol Biol. 2023 Dec;69(6):610-611. doi: 10.1165/rcmb.2023-0301ED. PubMed PMID: 37672661; PubMed Central PMCID: PMC10704122.

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Gladstone DE, D'Alessio F, Howard C, Lyu MA, Mock JR, Gibbs KW, Abrams D, Huang M, Zeng K, Herlihy JP, Castillo ST, Bassett R, Sadeghi T, Parmar S, Flowers CR, Mukherjee S, Schoenfeld D, Thall PF, Slutsky AS. Randomized, double-blinded, placebo-controlled trial of allogeneic cord blood T-regulatory cells for treatment of COVID-19 ARDS. Blood Adv. 2023 Jul 11;7(13):3075-3079. doi: 10.1182/bloodadvances.2022009619. PubMed PMID: 36961352; PubMed Central PMCID: PMC10043947.

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Del Rosario O, Suresh K, Kallem M, Singh G, Shah A, Zheng L, Yun X, Philip NM, Putcha N, McClure MB, Jiang H, D'Alessio F, Srivastava M, Bera A, Shimoda LA, Merchant M, Rane MJ, Machamer CE, Mock J, Hagan R, Koch AL, Punjabi NM, Kolb TM, Damarla M. MK2 nonenzymatically promotes nuclear translocation of caspase-3 and resultant apoptosis. Am J Physiol Lung Cell Mol Physiol. 2023 May 1;324(5):L700-L711. doi: 10.1152/ajplung.00340.2022. Epub 2023 Mar 28. PubMed PMID: 36976920; PubMed Central PMCID: PMC10190840.

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Suresh K, Del Rosario O, Kallem M, Singh G, Shah A, Zheng L, Yun X, Philip NM, Putcha N, McClure MB, Jiang H, D'Alessio F, Srivastava M, Bera A, Shimoda LA, Merchant M, Rane MJ, Machamer CE, Mock J, Hagan R, Koch AL, Punjabi NM, Kolb TM, Damarla M. Tumor MK2 transcript levels are associated with improved response to chemotherapy and patient survival in non-small cell lung cancer. Physiol Genomics. 2023 Apr 1;55(4):168-178. doi: 10.1152/physiolgenomics.00155.2022. Epub 2023 Mar 6. PubMed PMID: 36878491; PubMed Central PMCID: PMC10042611.

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Mock JR, Tune MK, Bose PG, McCullough MJ, Doerschuk CM. Comparison of different methods of initiating lung inflammation and the sex-specific effects on inflammatory parameters. Am J Physiol Lung Cell Mol Physiol. 2023 Feb 1;324(2):L199-L210. doi: 10.1152/ajplung.00118.2022. Epub 2023 Jan 3. PubMed PMID: 36594854; PubMed Central PMCID: PMC9925158.

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The effect of endogenous and exogenous glucocorticoids acting through regulatory T cells on resolution of ALI and the contribution of host genetic variability. 2023 June. DOI: 10.48321/D1292F.

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Dinnon KH 3rd, Leist SR, Okuda K, Dang H, Fritch EJ, Gully KL, De la Cruz G, Evangelista MD, Asakura T, Gilmore RC, Hawkins P, Nakano S, West A, Schäfer A, Gralinski LE, Everman JL, Sajuthi SP, Zweigart MR, Dong S, McBride J, Cooley MR, Hines JB, Love MK, Groshong SD, VanSchoiack A, Phelan SJ, Liang Y, Hether T, Leon M, Zumwalt RE, Barton LM, Duval EJ, Mukhopadhyay S, Stroberg E, Borczuk A, Thorne LB, Sakthivel MK, Lee YZ, Hagood JS, Mock JR, Seibold MA, O'Neal WK, Montgomery SA, Boucher RC, Baric RS. SARS-CoV-2 infection produces chronic pulmonary epithelial and immune cell dysfunction with fibrosis in mice. Sci Transl Med. 2022 Sep 28;14(664):eabo5070. doi: 10.1126/scitranslmed.abo5070. Epub 2022 Sep 28. PubMed PMID: 35857635; PubMed Central PMCID: PMC9273046.

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Murray B, Sikora A, Mock JR, Devlin T, Keats K, Powell R, Bice T. Reverse Triggering: An Introduction to Diagnosis, Management, and Pharmacologic Implications. Front Pharmacol. 2022;13:879011. doi: 10.3389/fphar.2022.879011. eCollection 2022. Review. PubMed PMID: 35814233; PubMed Central PMCID: PMC9256988.

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McDonald JT, Enguita FJ, Taylor D, Griffin RJ, Priebe W, Emmett MR, Sajadi MM, Harris AD, Clement J, Dybas JM, Aykin-Burns N, Guarnieri JW, Singh LN, Grabham P, Baylin SB, Yousey A, Pearson AN, Corry PM, Saravia-Butler A, Aunins TR, Sharma S, Nagpal P, Meydan C, Foox J, Mozsary C, Cerqueira B, Zaksas V, Singh U, Wurtele ES, Costes SV, Davanzo GG, Galeano D, Paccanaro A, Meinig SL, Hagan RS, Bowman NM, Wolfgang MC, Altinok S, Sapoval N, Treangen TJ, Moraes-Vieira PM, Vanderburg C, Wallace DC, Schisler JC, Mason CE, Chatterjee A, Meller R, Beheshti A. Role of miR-2392 in driving SARS-CoV-2 infection. Cell Rep. 2021 Oct 19;37(3):109839. doi: 10.1016/j.celrep.2021.109839. Epub 2021 Sep 30. PubMed PMID: 34624208; PubMed Central PMCID: PMC8481092.

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Friedman E, Franzone J, Ko ER, Corey K, Mock J, Alavian N, Schwartz A, Drummond MB, Suber T, Linstrum K, Bain W, Castiblanco SA, Zak M, Zaeh S, Gupta I, Damarla M, Punjabi NM. Rationale and design of the Prone Position and Respiratory Outcomes in Non-intubated COVID-19 PatiEnts: The "PRONE" Study. Contemp Clin Trials. 2021 Oct;109:106541. doi: 10.1016/j.cct.2021.106541. Epub 2021 Aug 13. PubMed PMID: 34400361; PubMed Central PMCID: PMC8363159.

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Sanders EC, Burkes RM, Mock JR, Brown TT, Wise RA, Hansel NN, Liu MC, Drummond MB. Bronchoalveolar Lavage and Plasma Cathelicidin Response to 25-Hydroxy Vitamin D Supplementation: A Pilot Study. Chronic Obstr Pulm Dis. 2021 Jul 28;8(3):371-381. doi: 10.15326/jcopdf.2021.0220. PubMed PMID: 34044475; PubMed Central PMCID: PMC8428594.

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Norton DL, Ceppe A, Tune MK, McCravy M, Devlin T, Drummond MB, Carson SS, Vincent BG, Hagan RS, Dang H, Doerschuk CM, Mock JR. Bronchoalveolar Tregs are associated with duration of mechanical ventilation in acute respiratory distress syndrome. J Transl Med. 2020 Nov 11;18(1):427. doi: 10.1186/s12967-020-02595-3. PubMed PMID: 33176790; PubMed Central PMCID: PMC7656499.

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Hedrick TL, Murray BP, Hagan RS, Mock JR. COVID-19: Clean up on IL-6. Am J Respir Cell Mol Biol. 2020 Oct;63(4):541-543. doi: 10.1165/rcmb.2020-0277LE. PubMed PMID: 32750259; PubMed Central PMCID: PMC7528925.

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Mock JR, Dial CF, Tune MK, Gilmore RC, O'Neal WK, Dang H, Doerschuk CM. Impact of Regulatory T Cells on Type 2 Alveolar Epithelial Cell Transcriptomes during Resolution of Acute Lung Injury and Contributions of IFN-γ. Am J Respir Cell Mol Biol. 2020 Oct;63(4):464-477. doi: 10.1165/rcmb.2019-0399OC. PubMed PMID: 32543909; PubMed Central PMCID: PMC7528916.

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Laudermilk LT, Tovar A, Homstad AK, Thomas JM, McFadden KM, Tune MK, Cowley DO, Mock JR, Ideraabdullah F, Kelada SNP. Baseline and innate immune response characterization of a Zfp30 knockout mouse strain. Mamm Genome. 2020 Aug;31(7-8):205-214. doi: 10.1007/s00335-020-09847-z. Epub 2020 Aug 29. PubMed PMID: 32860515; PubMed Central PMCID: PMC7486244.

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Mock JR, Tune MK, Dial CF, Torres-Castillo J, Hagan RS, Doerschuk CM. Effects of IFN-γ on immune cell kinetics during the resolution of acute lung injury. Physiol Rep. 2020 Feb;8(3):e14368. doi: 10.14814/phy2.14368. PubMed PMID: 32061190; PubMed Central PMCID: PMC7023890.

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Mock JR, Dial CF, Tune MK, Norton DL, Martin JR, Gomez JC, Hagan RS, Dang H, Doerschuk CM. Transcriptional analysis of Foxp3+ Tregs and functions of two identified molecules during resolution of ALI. JCI Insight. 2019 Mar 21;4(6). doi: 10.1172/jci.insight.124958. eCollection 2019 Mar 21. PubMed PMID: 30753170; PubMed Central PMCID: PMC6482998.

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Gomez JC, Dang H, Kanke M, Hagan RS, Mock JR, Kelada SNP, Sethupathy P, Doerschuk CM. Predicted effects of observed changes in the mRNA and microRNA transcriptome of lung neutrophils during S. pneumoniae pneumonia in mice. Sci Rep. 2017 Sep 12;7(1):11258. doi: 10.1038/s41598-017-11638-7. PubMed PMID: 28900269; PubMed Central PMCID: PMC5595893.

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Dial CF, Tune MK, Doerschuk CM, Mock JR. Foxp3(+) Regulatory T Cell Expression of Keratinocyte Growth Factor Enhances Lung Epithelial Proliferation. Am J Respir Cell Mol Biol. 2017 Aug;57(2):162-173. doi: 10.1165/rcmb.2017-0019OC. PubMed PMID: 28296468; PubMed Central PMCID: PMC5576587.

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Mock J, Singer B, D’Alessio F. Flow Cytometric Evaluation of Acute Lung Injury and Repair. In: Respiratory Medicine [Internet] Cham: Springer International Publishing; 2017. Chapter Chapter 7; 85-106p. Available from: http://link.springer.com/10.1007/978-3-319-46527-2_7.

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Mock JR, Kolb TM, Illei PB, Yang SC, Lederman HM, Merlo CA. Bronchus-associated Lymphoid Tissue in Kabuki Syndrome with Associated Hyper-IgM Syndrome/Common Variable Immunodeficiency. Am J Respir Crit Care Med. 2016 Aug 15;194(4):514-5. doi: 10.1164/rccm.201511-2305IM. PubMed PMID: 27275756; PubMed Central PMCID: PMC5803647.

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Singer BD, Mock JR, D'Alessio FR, Aggarwal NR, Mandke P, Johnston L, Damarla M. Flow-cytometric method for simultaneous analysis of mouse lung epithelial, endothelial, and hematopoietic lineage cells. Am J Physiol Lung Cell Mol Physiol. 2016 May 1;310(9):L796-801. doi: 10.1152/ajplung.00334.2015. Epub 2016 Mar 4. PubMed PMID: 26944088; PubMed Central PMCID: PMC4867353.

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Aggarwal NR, Tsushima K, Eto Y, Tripathi A, Mandke P, Mock JR, Garibaldi BT, Singer BD, Sidhaye VK, Horton MR, King LS, D'Alessio FR. Correction: Immunological Priming Requires Regulatory T Cells and IL-10-Producing Macrophages To Accelerate Resolution from Severe Lung Inflammation. J Immunol. 2016 May 1;196(9):3963-5. doi: 10.4049/jimmunol.1600348. PubMed PMID: 27183650.

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D'Alessio FR, Craig JM, Singer BD, Files DC, Mock JR, Garibaldi BT, Fallica J, Tripathi A, Mandke P, Gans JH, Limjunyawong N, Sidhaye VK, Heller NM, Mitzner W, King LS, Aggarwal NR. Enhanced resolution of experimental ARDS through IL-4-mediated lung macrophage reprogramming. Am J Physiol Lung Cell Mol Physiol. 2016 Apr 15;310(8):L733-46. doi: 10.1152/ajplung.00419.2015. Epub 2016 Feb 19. PubMed PMID: 26895644; PubMed Central PMCID: PMC4836113.

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Kolb TM, Peabody J, Baddoura P, Fallica J, Mock JR, Singer BD, D'Alessio FR, Damarla M, Damico RL, Hassoun PM. Right Ventricular Angiogenesis is an Early Adaptive Response to Chronic Hypoxia-Induced Pulmonary Hypertension. Microcirculation. 2015 Nov;22(8):724-36. doi: 10.1111/micc.12247. PubMed PMID: 26352923; PubMed Central PMCID: PMC4715581.

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Limjunyawong N, Mock J, Mitzner W. Instillation and Fixation Methods Useful in Mouse Lung Cancer Research. J Vis Exp. 2015 Aug 31;(102):e52964. doi: 10.3791/52964. PubMed PMID: 26381993; PubMed Central PMCID: PMC4692577.

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Singer BD, Mock JR, Aggarwal NR, Garibaldi BT, Sidhaye VK, Florez MA, Chau E, Gibbs KW, Mandke P, Tripathi A, Yegnasubramanian S, King LS, D'Alessio FR. Regulatory T cell DNA methyltransferase inhibition accelerates resolution of lung inflammation. Am J Respir Cell Mol Biol. 2015 May;52(5):641-52. doi: 10.1165/rcmb.2014-0327OC. PubMed PMID: 25295995; PubMed Central PMCID: PMC4491142.

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Files DC, Liu C, Pereyra A, Wang ZM, Aggarwal NR, D'Alessio FR, Garibaldi BT, Mock JR, Singer BD, Feng X, Yammani RR, Zhang T, Lee AL, Philpott S, Lussier S, Purcell L, Chou J, Seeds M, King LS, Morris PE, Delbono O. Therapeutic exercise attenuates neutrophilic lung injury and skeletal muscle wasting. Sci Transl Med. 2015 Mar 11;7(278):278ra32. doi: 10.1126/scitranslmed.3010283. PubMed PMID: 25761888; PubMed Central PMCID: PMC4820823.

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Mock JR, Garibaldi BT, Aggarwal NR, Jenkins J, Limjunyawong N, Singer BD, Chau E, Rabold R, Files DC, Sidhaye V, Mitzner W, Wagner EM, King LS, D'Alessio FR. Foxp3+ regulatory T cells promote lung epithelial proliferation. Mucosal Immunol. 2014 Nov;7(6):1440-51. doi: 10.1038/mi.2014.33. Epub 2014 May 21. PubMed PMID: 24850425; PubMed Central PMCID: PMC4205163.

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Aggarwal NR, Tsushima K, Eto Y, Tripathi A, Mandke P, Mock JR, Garibaldi BT, Singer BD, Sidhaye VK, Horton MR, King LS, D'Alessio FR. Immunological priming requires regulatory T cells and IL-10-producing macrophages to accelerate resolution from severe lung inflammation. J Immunol. 2014 May 1;192(9):4453-4464. doi: 10.4049/jimmunol.1400146. Epub 2014 Mar 31. PubMed PMID: 24688024; PubMed Central PMCID: PMC4001810.

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Aggarwal NR, Chau E, Garibaldi BT, Mock JR, Sussan T, Rao K, Rao K, Menon AG, D'Alessio FR, Damarla M, Biswal S, King LS, Sidhaye VK. Aquaporin 5 regulates cigarette smoke induced emphysema by modulating barrier and immune properties of the epithelium. Tissue Barriers. 2013 Oct 1;1(4):e25248. doi: 10.4161/tisb.25248. Epub 2013 Jun 3. PubMed PMID: 24665410; PubMed Central PMCID: PMC3783223.

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Aggarwal NR, D'Alessio FR, Eto Y, Chau E, Avalos C, Waickman AT, Garibaldi BT, Mock JR, Files DC, Sidhaye V, Polotsky VY, Powell J, Horton M, King LS. Macrophage A2A adenosinergic receptor modulates oxygen-induced augmentation of murine lung injury. Am J Respir Cell Mol Biol. 2013 May;48(5):635-46. doi: 10.1165/rcmb.2012-0351OC. PubMed PMID: 23349051; PubMed Central PMCID: PMC3707379.

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Yao Q, Shin MK, Jun JC, Hernandez KL, Aggarwal NR, Mock JR, Gay J, Drager LF, Polotsky VY. Effect of chronic intermittent hypoxia on triglyceride uptake in different tissues. J Lipid Res. 2013 Apr;54(4):1058-65. doi: 10.1194/jlr.M034272. Epub 2013 Feb 5. PubMed PMID: 23386706; PubMed Central PMCID: PMC3605982.

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Hoang MT, Mock JR, Hoang MP, Cohen JB, Le LQ. An exophytic, bleeding nodule on the left malar region. Clin Exp Dermatol. 2013 Mar;38(2):217-8. doi: 10.1111/j.1365-2230.2012.04400.x. Epub 2012 Jun 8. PubMed PMID: 22681240.

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Garibaldi BT, D'Alessio FR, Mock JR, Files DC, Chau E, Eto Y, Drummond MB, Aggarwal NR, Sidhaye V, King LS. Regulatory T cells reduce acute lung injury fibroproliferation by decreasing fibrocyte recruitment. Am J Respir Cell Mol Biol. 2013 Jan;48(1):35-43. doi: 10.1165/rcmb.2012-0198OC. Epub 2012 Sep 20. PubMed PMID: 23002097; PubMed Central PMCID: PMC3547087.

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D'Alessio FR, Tsushima K, Aggarwal NR, Mock JR, Eto Y, Garibaldi BT, Files DC, Avalos CR, Rodriguez JV, Waickman AT, Reddy SP, Pearse DB, Sidhaye VK, Hassoun PM, Crow MT, King LS. Resolution of experimental lung injury by monocyte-derived inducible nitric oxide synthase. J Immunol. 2012 Sep 1;189(5):2234-45. doi: 10.4049/jimmunol.1102606. Epub 2012 Jul 27. PubMed PMID: 22844117; PubMed Central PMCID: PMC3424351.

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Files DC, D'Alessio FR, Johnston LF, Kesari P, Aggarwal NR, Garibaldi BT, Mock JR, Simmers JL, DeGorordo A, Murdoch J, Willis MS, Patterson C, Tankersley CG, Messi ML, Liu C, Delbono O, Furlow JD, Bodine SC, Cohn RD, King LS, Crow MT. A critical role for muscle ring finger-1 in acute lung injury-associated skeletal muscle wasting. Am J Respir Crit Care Med. 2012 Apr 15;185(8):825-34. doi: 10.1164/rccm.201106-1150OC. Epub 2012 Feb 3. PubMed PMID: 22312013; PubMed Central PMCID: PMC3360571.

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Labandeira-Rey M, Mock JR, Hansen EJ. Regulation of expression of the Haemophilus ducreyi LspB and LspA2 proteins by CpxR. Infect Immun. 2009 Aug;77(8):3402-11. doi: 10.1128/IAI.00292-09. Epub 2009 May 18. PubMed PMID: 19451237; PubMed Central PMCID: PMC2715676.

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Deng K, Mock JR, Greenberg S, van Oers NS, Hansen EJ. Haemophilus ducreyi LspA proteins are tyrosine phosphorylated by macrophage-encoded protein tyrosine kinases. Infect Immun. 2008 Oct;76(10):4692-702. doi: 10.1128/IAI.00513-08. Epub 2008 Aug 4. PubMed PMID: 18678665; PubMed Central PMCID: PMC2546853.

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Mock JR, Vakevainen M, Deng K, Latimer JL, Young JA, van Oers NS, Greenberg S, Hansen EJ. Haemophilus ducreyi targets Src family protein tyrosine kinases to inhibit phagocytic signaling. Infect Immun. 2005 Dec;73(12):7808-16. doi: 10.1128/IAI.73.12.7808-7816.2005. PubMed PMID: 16299270; PubMed Central PMCID: PMC1307070.

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Ward CK, Mock JR, Hansen EJ. The LspB protein is involved in the secretion of the LspA1 and LspA2 proteins by Haemophilus ducreyi. Infect Immun. 2004 Apr;72(4):1874-84. doi: 10.1128/IAI.72.4.1874-1884.2004. PubMed PMID: 15039306; PubMed Central PMCID: PMC375143.

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Spinola SM, Fortney KR, Katz BP, Latimer JL, Mock JR, Vakevainen M, Hansen EJ. Haemophilus ducreyi requires an intact flp gene cluster for virulence in humans. Infect Immun. 2003 Dec;71(12):7178-82. doi: 10.1128/IAI.71.12.7178-7182.2003. PubMed PMID: 14638812; PubMed Central PMCID: PMC308926.

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Ward CK, Latimer JL, Nika J, Vakevainen M, Mock JR, Deng K, Blick RJ, Hansen EJ. Mutations in the lspA1 and lspA2 genes of Haemophilus ducreyi affect the virulence of this pathogen in an animal model system. Infect Immun. 2003 May;71(5):2478-86. doi: 10.1128/IAI.71.5.2478-2486.2003. PubMed PMID: 12704119; PubMed Central PMCID: PMC153216.