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Rickard BP, Overchuk M, Tulino J, Tan X, Ligler FS, Bae-Jump VL, Fenton SE, Rizvi I. Exposure to select PFAS and PFAS mixtures alters response to platinum-based chemotherapy in endometrial cancer cell lines. Environ Health. 2023 Dec 14;22(1):87. doi: 10.1186/s12940-023-01034-2. PubMed PMID: 38098045; PubMed Central PMCID: PMC10720226.
Liang BJ, Pang S, Perttila R, Ma CH, Srivastava P, Gaitan B, Sorrin AJ, Fadul N, Rahman I, Yl Formula See Text Niemi Z, Roque DM, Hasan T, Uusimaa P, Huang HC. Fluorescence-guided photoimmunotherapy using targeted nanotechnology and ML7710 to manage peritoneal carcinomatosis. Sci Adv. 2023 Sep 8;9(36):eadi3441. doi: 10.1126/sciadv.adi3441. Epub 2023 Sep 6. PubMed PMID: 37672582; PubMed Central PMCID: PMC10482332.
Sorrin AJ, Zhou K, May K, Liu C, McNaughton K, Rahman I, Liang BJ, Rizvi I, Roque DM, Huang HC. Transient fluid flow improves photoimmunoconjugate delivery and photoimmunotherapy efficacy. iScience. 2023 Aug 18;26(8):107221. doi: 10.1016/j.isci.2023.107221. eCollection 2023 Aug 18. PubMed PMID: 37520715; PubMed Central PMCID: PMC10372742.
Rickard BP, Overchuk M, Obaid G, Ruhi MK, Demirci U, Fenton SE, Santos JH, Kessel D, Rizvi I. Photochemical Targeting of Mitochondria to Overcome Chemoresistance in Ovarian Cancer (†). Photochem Photobiol. 2023 Mar;99(2):448-468. doi: 10.1111/php.13723. Epub 2022 Oct 19. Review. PubMed PMID: 36117466; PubMed Central PMCID: PMC10043796.
Rickard BP, Tan X, Fenton SE, Rizvi I. Photodynamic Priming Overcomes Per- and Polyfluoroalkyl Substance (PFAS)-Induced Platinum Resistance in Ovarian Cancer(†). Photochem Photobiol. 2023 Mar;99(2):793-813. doi: 10.1111/php.13728. Epub 2022 Nov 7. PubMed PMID: 36148678; PubMed Central PMCID: PMC10033467.
Karimnia V, Stanley ME, Fitzgerald CT, Rizvi I, Slack FJ, Celli JP. Photodynamic Stromal Depletion Enhances Therapeutic Nanoparticle Delivery in 3D Pancreatic Ductal Adenocarcinoma Tumor Models. Photochem Photobiol. 2023 Jan;99(1):120-131. doi: 10.1111/php.13663. Epub 2022 Aug 3. PubMed PMID: 35699307; PubMed Central PMCID: PMC10082669.
Conrad C, Conway J, Polacheck WJ, Rizvi I, Scarcelli G. Water transport regulates nucleus volume, cell density, Young's modulus, and E-cadherin expression in tumor spheroids. Eur J Cell Biol. 2022 Sep-Nov;101(4):151278. doi: 10.1016/j.ejcb.2022.151278. Epub 2022 Oct 21. PubMed PMID: 36306595.
Kessel D, Obaid G, Rizvi I. Critical PDT theory II: Current concepts and indications. Photodiagnosis Photodyn Ther. 2022 Sep;39:102923. doi: 10.1016/j.pdpdt.2022.102923. Epub 2022 May 21. PubMed PMID: 35605924; PubMed Central PMCID: PMC9458629.
Rickard BP, Tan X, Fenton SE, Rizvi I. Select Per- and Polyfluoroalkyl Substances (PFAS) Induce Resistance to Carboplatin in Ovarian Cancer Cell Lines. Int J Mol Sci. 2022 May 5;23(9). doi: 10.3390/ijms23095176. PubMed PMID: 35563566; PubMed Central PMCID: PMC9104343.
Rickard BP, Rizvi I, Fenton SE. Per- and poly-fluoroalkyl substances (PFAS) and female reproductive outcomes: PFAS elimination, endocrine-mediated effects, and disease. Toxicology. 2022 Jan 15;465:153031. doi: 10.1016/j.tox.2021.153031. Epub 2021 Nov 10. Review. PubMed PMID: 34774661; PubMed Central PMCID: PMC8743032.
Conrad C, Moore K, Polacheck W, Rizvi I, Scarcelli G. Mechanical Modulation of Ovarian Cancer Tumor Nodules Under Flow. IEEE Trans Biomed Eng. 2022 Jan;69(1):294-301. doi: 10.1109/TBME.2021.3092641. Epub 2021 Dec 23. PubMed PMID: 34170820; PubMed Central PMCID: PMC8750319.
Rickard BP, Conrad C, Sorrin AJ, Ruhi MK, Reader JC, Huang SA, Franco W, Scarcelli G, Polacheck WJ, Roque DM, Del Carmen MG, Huang HC, Demirci U, Rizvi I. Malignant Ascites in Ovarian Cancer: Cellular, Acellular, and Biophysical Determinants of Molecular Characteristics and Therapy Response. Cancers (Basel). 2021 Aug 26;13(17). doi: 10.3390/cancers13174318. Review. PubMed PMID: 34503128; PubMed Central PMCID: PMC8430600.
Soto F, Guimarães CF, Reis RL, Franco W, Rizvi I, Demirci U. Emerging biofabrication approaches for gastrointestinal organoids towards patient specific cancer models. Cancer Lett. 2021 Apr 28;504:116-124. doi: 10.1016/j.canlet.2021.01.023. Epub 2021 Feb 9. Review. PubMed PMID: 33577978.
Karimnia V, Rizvi I, Slack FJ, Celli JP. Photodestruction of Stromal Fibroblasts Enhances Tumor Response to PDT in 3D Pancreatic Cancer Coculture Models. Photochem Photobiol. 2021 Mar;97(2):416-426. doi: 10.1111/php.13339. Epub 2020 Oct 27. PubMed PMID: 33011973; PubMed Central PMCID: PMC7965253.
Anbil S, Pigula M, Huang HC, Mallidi S, Broekgaarden M, Baglo Y, De Silva P, Simeone DM, Mino-Kenudson M, Maytin EV, Rizvi I, Hasan T. Vitamin D Receptor Activation and Photodynamic Priming Enables Durable Low-dose Chemotherapy. Mol Cancer Ther. 2020 Jun;19(6):1308-1319. doi: 10.1158/1535-7163.MCT-19-0791. Epub 2020 Mar 27. PubMed PMID: 32220968; PubMed Central PMCID: PMC7272264.
Broekgaarden M, Alkhateeb A, Bano S, Bulin AL, Obaid G, Rizvi I, Hasan T. Cabozantinib Inhibits Photodynamic Therapy-Induced Auto- and Paracrine MET Signaling in Heterotypic Pancreatic Microtumors. Cancers (Basel). 2020 May 29;12(6). doi: 10.3390/cancers12061401. PubMed PMID: 32485915; PubMed Central PMCID: PMC7352584.
Nath S, Pigula M, Khan AP, Hanna W, Ruhi MK, Dehkordy FM, Pushpavanam K, Rege K, Moore K, Tsujita Y, Conrad C, Inci F, Carmen MGD, Franco W, Celli JP, Demirci U, Hasan T, Huang HC, Rizvi I. Flow-induced Shear Stress Confers Resistance to Carboplatin in an Adherent Three-Dimensional Model for Ovarian Cancer: A Role for EGFR-Targeted Photoimmunotherapy Informed by Physical Stress. J Clin Med. 2020 Mar 28;9(4). doi: 10.3390/jcm9040924. PubMed PMID: 32231055; PubMed Central PMCID: PMC7230263.
Sorrin AJ, Kemal Ruhi M, Ferlic NA, Karimnia V, Polacheck WJ, Celli JP, Huang HC, Rizvi I. Photodynamic Therapy and the Biophysics of the Tumor Microenvironment. Photochem Photobiol. 2020 Mar;96(2):232-259. doi: 10.1111/php.13209. Epub 2020 Mar 5. Review. PubMed PMID: 31895481; PubMed Central PMCID: PMC7138751.
Kercher EM, Nath S, Rizvi I, Spring BQ. Cancer Cell-targeted and Activatable Photoimmunotherapy Spares T Cells in a 3D Coculture Model. Photochem Photobiol. 2020 Mar;96(2):295-300. doi: 10.1111/php.13153. Epub 2019 Oct 13. PubMed PMID: 31424560; PubMed Central PMCID: PMC7028482.
Broekgaarden M, Anbil S, Bulin AL, Obaid G, Mai Z, Baglo Y, Rizvi I, Hasan T. Modulation of redox metabolism negates cancer-associated fibroblasts-induced treatment resistance in a heterotypic 3D culture platform of pancreatic cancer. Biomaterials. 2019 Nov;222:119421. doi: 10.1016/j.biomaterials.2019.119421. Epub 2019 Aug 12. PubMed PMID: 31494503; PubMed Central PMCID: PMC6934357.
Conrad C, Gray KM, Stroka KM, Rizvi I, Scarcelli G. Mechanical Characterization of 3D Ovarian Cancer Nodules Using Brillouin Confocal Microscopy. Cell Mol Bioeng. 2019 Jun;12(3):215-226. doi: 10.1007/s12195-019-00570-7. eCollection 2019 Jun. PubMed PMID: 31719911; PubMed Central PMCID: PMC6816613.
Spring BQ, Lang RT, Kercher EM, Rizvi I, Wenham RM, Conejo-Garcia JR, Hasan T, Gatenby RA, Enderling H. Illuminating the Numbers: Integrating Mathematical Models to Optimize Photomedicine Dosimetry and Combination Therapies. Front Phys. 2019 Apr;7. doi: 10.3389/fphy.2019.00046. Epub 2019 Apr 2. PubMed PMID: 31123672; PubMed Central PMCID: PMC6529192.
Rizvi I, Nath S, Obaid G, Ruhi MK, Moore K, Bano S, Kessel D, Hasan T. A Combination of Visudyne and a Lipid-anchored Liposomal Formulation of Benzoporphyrin Derivative Enhances Photodynamic Therapy Efficacy in a 3D Model for Ovarian Cancer. Photochem Photobiol. 2019 Jan;95(1):419-429. doi: 10.1111/php.13066. Epub 2019 Jan 7. PubMed PMID: 30499113; PubMed Central PMCID: PMC7473467.
Rizvi I, Obaid G, Bano S, Hasan T, Kessel D. Photodynamic therapy: Promoting in vitro efficacy of photodynamic therapy by liposomal formulations of a photosensitizing agent. Lasers Surg Med. 2018 Jul;50(5):499-505. doi: 10.1002/lsm.22813. Epub 2018 Mar 11. PubMed PMID: 29527710; PubMed Central PMCID: PMC7449601.
Broekgaarden M, Rizvi I, Bulin AL, Petrovic L, Goldschmidt R, Massodi I, Celli JP, Hasan T. Neoadjuvant photodynamic therapy augments immediate and prolonged oxaliplatin efficacy in metastatic pancreatic cancer organoids. Oncotarget. 2018 Feb 27;9(16):13009-13022. doi: 10.18632/oncotarget.24425. eCollection 2018 Feb 27. PubMed PMID: 29560127; PubMed Central PMCID: PMC5849191.
Huang HC, Liu J, Baglo Y, Rizvi I, Anbil S, Pigula M, Hasan T. Mechanism-informed Repurposing of Minocycline Overcomes Resistance to Topoisomerase Inhibition for Peritoneal Carcinomatosis. Mol Cancer Ther. 2018 Feb;17(2):508-520. doi: 10.1158/1535-7163.MCT-17-0568. Epub 2017 Nov 22. PubMed PMID: 29167313; PubMed Central PMCID: PMC5805648.
Huang HC, Rizvi I, Liu J, Anbil S, Kalra A, Lee H, Baglo Y, Paz N, Hayden D, Pereira S, Pogue BW, Fitzgerald J, Hasan T. Photodynamic Priming Mitigates Chemotherapeutic Selection Pressures and Improves Drug Delivery. Cancer Res. 2018 Jan 15;78(2):558-571. doi: 10.1158/0008-5472.CAN-17-1700. Epub 2017 Nov 29. PubMed PMID: 29187403; PubMed Central PMCID: PMC5771811.
Huang HC, Mallidi S, Liu J, Chiang CT, Mai Z, Goldschmidt R, Ebrahim-Zadeh N, Rizvi I, Hasan T. Photodynamic Therapy Synergizes with Irinotecan to Overcome Compensatory Mechanisms and Improve Treatment Outcomes in Pancreatic Cancer. Cancer Res. 2016 Mar 1;76(5):1066-77. doi: 10.1158/0008-5472.CAN-15-0391. Epub 2015 Dec 30. PubMed PMID: 26719532; PubMed Central PMCID: PMC4775276.
Spring BQ, Rizvi I, Xu N, Hasan T. The role of photodynamic therapy in overcoming cancer drug resistance. Photochem Photobiol Sci. 2015 Aug;14(8):1476-91. doi: 10.1039/c4pp00495g. Epub 2015 Apr 9. Review. PubMed PMID: 25856800; PubMed Central PMCID: PMC4520758.
Hempstead J, Jones DP, Ziouche A, Cramer GM, Rizvi I, Arnason S, Hasan T, Celli JP. Low-cost photodynamic therapy devices for global health settings: Characterization of battery-powered LED performance and smartphone imaging in 3D tumor models. Sci Rep. 2015 May 12;5:10093. doi: 10.1038/srep10093. PubMed PMID: 25965295; PubMed Central PMCID: PMC4428052.
Mallidi S, Mai Z, Rizvi I, Hempstead J, Arnason S, Celli J, Hasan T. In vivo evaluation of battery-operated light-emitting diode-based photodynamic therapy efficacy using tumor volume and biomarker expression as endpoints. J Biomed Opt. 2015 Apr;20(4):048003. doi: 10.1117/1.JBO.20.4.048003. PubMed PMID: 25909707; PubMed Central PMCID: PMC4408448.
Ghogare AA, Rizvi I, Hasan T, Greer A. "Pointsource" delivery of a photosensitizer drug and singlet oxygen: eradication of glioma cells in vitro. Photochem Photobiol. 2014 Sep-Oct;90(5):1119-25. doi: 10.1111/php.12274. Epub 2014 Apr 21. PubMed PMID: 24673689; PubMed Central PMCID: PMC4198175.
Spring BQ, Abu-Yousif AO, Palanisami A, Rizvi I, Zheng X, Mai Z, Anbil S, Sears RB, Mensah LB, Goldschmidt R, Erdem SS, Oliva E, Hasan T. Selective treatment and monitoring of disseminated cancer micrometastases in vivo using dual-function, activatable immunoconjugates. Proc Natl Acad Sci U S A. 2014 Mar 11;111(10):E933-42. doi: 10.1073/pnas.1319493111. Epub 2014 Feb 26. PubMed PMID: 24572574; PubMed Central PMCID: PMC3956156.
Celli JP, Rizvi I, Blanden AR, Massodi I, Glidden MD, Pogue BW, Hasan T. An imaging-based platform for high-content, quantitative evaluation of therapeutic response in 3D tumour models. Sci Rep. 2014 Jan 17;4:3751. doi: 10.1038/srep03751. PubMed PMID: 24435043; PubMed Central PMCID: PMC3894557.
Anbil S, Rizvi I, Celli JP, Alagic N, Pogue BW, Hasan T. Impact of treatment response metrics on photodynamic therapy planning and outcomes in a three-dimensional model of ovarian cancer. J Biomed Opt. 2013 Sep;18(9):098004. doi: 10.1117/1.JBO.18.9.098004. PubMed PMID: 24802230; PubMed Central PMCID: PMC3783041.
Rizvi I, Anbil S, Alagic N, Celli J, Zheng LZ, Palanisami A, Glidden MD, Pogue BW, Hasan T. PDT dose parameters impact tumoricidal durability and cell death pathways in a 3D ovarian cancer model. Photochem Photobiol. 2013 Jul-Aug;89(4):942-52. doi: 10.1111/php.12065. Epub 2013 Apr 4. PubMed PMID: 23442192; PubMed Central PMCID: PMC3701746.
Rizvi I, Gurkan UA, Tasoglu S, Alagic N, Celli JP, Mensah LB, Mai Z, Demirci U, Hasan T. Flow induces epithelial-mesenchymal transition, cellular heterogeneity and biomarker modulation in 3D ovarian cancer nodules. Proc Natl Acad Sci U S A. 2013 May 28;110(22):E1974-83. doi: 10.1073/pnas.1216989110. Epub 2013 May 3. PubMed PMID: 23645635; PubMed Central PMCID: PMC3670329.
Glidden MD, Celli JP, Massodi I, Rizvi I, Pogue BW, Hasan T. Image-Based Quantification of Benzoporphyrin Derivative Uptake, Localization, and Photobleaching in 3D Tumor Models, for Optimization of PDT Parameters. Theranostics. 2012;2(9):827-39. doi: 10.7150/thno.4334. Epub 2012 Sep 5. PubMed PMID: 23082096; PubMed Central PMCID: PMC3475211.
Rizvi I, Dinh TA, Yu W, Chang Y, Sherwood ME, Hasan T. Photoimmunotherapy and irradiance modulation reduce chemotherapy cycles and toxicity in a murine model for ovarian carcinomatosis: perspective and results. Isr J Chem. 2012 Sep;52(8-9):776-787. doi: 10.1002/ijch.201200016. PubMed PMID: 23626376; PubMed Central PMCID: PMC3634612.
Evans CL, Abu-Yousif AO, Park YJ, Klein OJ, Celli JP, Rizvi I, Zheng X, Hasan T. Killing hypoxic cell populations in a 3D tumor model with EtNBS-PDT. PLoS One. 2011;6(8):e23434. doi: 10.1371/journal.pone.0023434. Epub 2011 Aug 18. PubMed PMID: 21876751; PubMed Central PMCID: PMC3158086.
Xu F, Celli J, Rizvi I, Moon S, Hasan T, Demirci U. A three-dimensional in vitro ovarian cancer coculture model using a high-throughput cell patterning platform. Biotechnol J. 2011 Feb;6(2):204-212. doi: 10.1002/biot.201000340. PubMed PMID: 21298805; PubMed Central PMCID: PMC3780785.
Rahmanzadeh R, Rai P, Celli JP, Rizvi I, Baron-Lühr B, Gerdes J, Hasan T. Ki-67 as a molecular target for therapy in an in vitro three-dimensional model for ovarian cancer. Cancer Res. 2010 Nov 15;70(22):9234-42. doi: 10.1158/0008-5472.CAN-10-1190. Epub 2010 Nov 2. PubMed PMID: 21045152; PubMed Central PMCID: PMC3057762.
Rizvi I, Celli JP, Evans CL, Abu-Yousif AO, Muzikansky A, Pogue BW, Finkelstein D, Hasan T. Synergistic enhancement of carboplatin efficacy with photodynamic therapy in a three-dimensional model for micrometastatic ovarian cancer. Cancer Res. 2010 Nov 15;70(22):9319-28. doi: 10.1158/0008-5472.CAN-10-1783. Epub 2010 Nov 9. PubMed PMID: 21062986; PubMed Central PMCID: PMC3057933.
Celli JP, Rizvi I, Evans CL, Abu-Yousif AO, Hasan T. Quantitative imaging reveals heterogeneous growth dynamics and treatment-dependent residual tumor distributions in a three-dimensional ovarian cancer model. J Biomed Opt. 2010 Sep-Oct;15(5):051603. doi: 10.1117/1.3483903. PubMed PMID: 21054077; PubMed Central PMCID: PMC2948043.
Celli JP, Spring BQ, Rizvi I, Evans CL, Samkoe KS, Verma S, Pogue BW, Hasan T. Imaging and photodynamic therapy: mechanisms, monitoring, and optimization. Chem Rev. 2010 May 12;110(5):2795-838. doi: 10.1021/cr900300p. Review. PubMed PMID: 20353192; PubMed Central PMCID: PMC2896821.
Samkoe KS, Chen A, Rizvi I, O'Hara JA, Hoopes PJ, Pereira SP, Hasan T, Pogue BW. Imaging tumor variation in response to photodynamic therapy in pancreatic cancer xenograft models. Int J Radiat Oncol Biol Phys. 2010 Jan 1;76(1):251-9. doi: 10.1016/j.ijrobp.2009.08.041. PubMed PMID: 20005458; PubMed Central PMCID: PMC2902770.
Abu-Yousif AO, Rizvi I, Evans CL, Celli JP, Hasan T. PuraMatrix encapsulation of cancer cells. J Vis Exp. 2009 Dec 17;(34). doi: 10.3791/1692. PubMed PMID: 20019656; PubMed Central PMCID: PMC3152243.
Zhong W, Celli JP, Rizvi I, Mai Z, Spring BQ, Yun SH, Hasan T. In vivo high-resolution fluorescence microendoscopy for ovarian cancer detection and treatment monitoring. Br J Cancer. 2009 Dec 15;101(12):2015-22. doi: 10.1038/sj.bjc.6605436. Epub 2009 Nov 17. PubMed PMID: 19920823; PubMed Central PMCID: PMC2795438.
Evans CL, Rizvi I, Hasan T, de Boer JF. In vitro ovarian tumor growth and treatment response dynamics visualized with time-lapse OCT imaging. Opt Express. 2009 May 25;17(11):8892-906. doi: 10.1364/oe.17.008892. PubMed PMID: 19466138; PubMed Central PMCID: PMC2836890.
Laubach HJ, Chang SK, Lee S, Rizvi I, Zurakowski D, Davis SJ, Taylor CR, Hasan T. In-vivo singlet oxygen dosimetry of clinical 5-aminolevulinic acid photodynamic therapy. J Biomed Opt. 2008 Sep-Oct;13(5):050504. doi: 10.1117/1.2981813. PubMed PMID: 19021376; PubMed Central PMCID: PMC2994192.
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