My Bibliography

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Fenton AD, Archin N, Turner A-M, Joseph S, Moeser M, Margolis DM, Browne EP. A novel high-throughput microwell outgrowth assay for HIV-infected cells. J Virol. 2024 Mar 19;98(3):e0179823. doi: 10.1128/jvi.01798-23. Epub 2024 Feb 20. PubMed PMID: 38376258; PubMed Central PMCID: PMC10949454.

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Bonner X, Sondgeroth A, McCue A, Nicely N, Tripathy A, Spielvogel E, Moeser M, Ke R, Leiderman K, Joseph SB, Swanstrom R. Stoichiometry for entry and binding properties of the Env protein of R5 T cell-tropic HIV-1 and its evolutionary variant of macrophage-tropic HIV-1. mBio. 2024 Mar 1;:e0032124. doi: 10.1128/mbio.00321-24. [Epub ahead of print] PubMed PMID: 38426750.

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Joseph SB, Abrahams MR, Moeser M, Tyers L, Archin NM, Council OD, Sondgeroth A, Spielvogel E, Emery A, Zhou S, Doolabh D, Ismail SD, Karim SA, Margolis DM, Pond SK, Garrett N, Swanstrom R, Williamson C. The timing of HIV-1 infection of cells that persist on therapy is not strongly influenced by replication competency or cellular tropism of the provirus. PLoS Pathog. 2024 Feb;20(2):e1011974. doi: 10.1371/journal.ppat.1011974. eCollection 2024 Feb. PubMed PMID: 38422171; PubMed Central PMCID: PMC10931466.

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Tang Y, Chaillon A, Gianella S, Wong LM, Li D, Simermeyer TL, Porrachia M, Ignacio C, Woodworth B, Zhong D, Du J, de la Parra Polina E, Kirchherr J, Allard B, Clohosey ML, Moeser M, Sondgeroth AL, Whitehill GD, Singh V, Dashti A, Smith DM, Eron JJ, Bar KJ, Chahroudi A, Joseph SB, Archin NM, Margolis DM, Jiang G. Brain microglia serve as a persistent HIV reservoir despite durable antiretroviral therapy. J Clin Invest. 2023 Jun 15;133(12). doi: 10.1172/JCI167417. PubMed PMID: 37317962; PubMed Central PMCID: PMC10266791.

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Joseph SB, Gianella S, Burdo TH, Cinque P, Gisslen M, Letendre S, Nath A, Morgello S, Ndhlovu LC, Spudich S. Biotypes of Central Nervous System Complications in People With Human Immunodeficiency Virus: Virology, Immunology, and Neuropathology. J Infect Dis. 2023 Mar 17;227(Suppl 1):S3-S15. doi: 10.1093/infdis/jiac370. PubMed PMID: 36930640; PubMed Central PMCID: PMC10022721.

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Kincer LP, Joseph SB, Gilleece MM, Hauser BM, Sizemore S, Zhou S, Di Germanio C, Zetterberg H, Fuchs D, Deeks SG, Spudich S, Gisslen M, Price RW, Swanstrom R. Rebound HIV-1 in cerebrospinal fluid after antiviral therapy interruption is mainly clonally amplified R5 T cell-tropic virus. Nat Microbiol. 2023 Feb;8(2):260-271. doi: 10.1038/s41564-022-01306-6. Epub 2023 Jan 30. PubMed PMID: 36717718; PubMed Central PMCID: PMC10201410.

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Perkins MV, Joseph SB, Dittmer DP, Mackman N. Cardiovascular Disease and Thrombosis in HIV Infection. Arterioscler Thromb Vasc Biol. 2023 Feb;43(2):175-191. doi: 10.1161/ATVBAHA.122.318232. Epub 2022 Dec 1. Review. PubMed PMID: 36453273; PubMed Central PMCID: PMC10165851.

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Kincer LP, Schnell G, Swanstrom R, Miller MB, Spudich S, Eron JJ, Price RW, Joseph SB. HIV-1 is Transported into the Central Nervous System by Trafficking Infected Cells. Pathog Immun. 2022;7(2):131-142. doi: 10.20411/pai.v7i2.524. eCollection 2022. PubMed PMID: 36865569; PubMed Central PMCID: PMC9973728.

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Woodburn BM, Kanchi K, Zhou S, Colaianni N, Joseph SB, Swanstrom R. Characterization of Macrophage-Tropic HIV-1 Infection of Central Nervous System Cells and the Influence of Inflammation. J Virol. 2022 Sep 14;96(17):e0095722. doi: 10.1128/jvi.00957-22. Epub 2022 Aug 17. PubMed PMID: 35975998; PubMed Central PMCID: PMC9472603.

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Gay CL, James KS, Tuyishime M, Falcinelli SD, Joseph SB, Moeser MJ, Allard B, Kirchherr JL, Clohosey M, Raines SLM, Montefiori DC, Shen X, Gorelick RJ, Gama L, McDermott AB, Koup RA, Mascola JR, Floris-Moore M, Kuruc JD, Ferrari G, Eron JJ, Archin NM, Margolis DM. Stable Latent HIV Infection and Low-level Viremia Despite Treatment With the Broadly Neutralizing Antibody VRC07-523LS and the Latency Reversal Agent Vorinostat. J Infect Dis. 2022 Mar 2;225(5):856-861. doi: 10.1093/infdis/jiab487. PubMed PMID: 34562096; PubMed Central PMCID: PMC8889279.

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Ismail SD, Riou C, Joseph SB, Archin NM, Margolis DM, Perelson AS, Cassidy T, Abrahams MR, Moeser M, Council OD, McKinnon LR, Osman F, Karim QA, Abdool Karim SS, Swanstrom R, Williamson C, Garrett NJ, Burgers WA. Immunological Correlates of the HIV-1 Replication-Competent Reservoir Size. Clin Infect Dis. 2021 Oct 20;73(8):1528-1531. doi: 10.1093/cid/ciab587. PubMed PMID: 34181706; PubMed Central PMCID: PMC8528395.

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Warren JA, Zhou S, Xu Y, Moeser MJ, MacMillan DR, Council O, Kirchherr J, Sung JM, Roan NR, Adimora AA, Joseph S, Kuruc JD, Gay CL, Margolis DM, Archin N, Brumme ZL, Swanstrom R, Goonetilleke N. The HIV-1 latent reservoir is largely sensitive to circulating T cells. Elife. 2020 Oct 6;9. doi: 10.7554/eLife.57246. PubMed PMID: 33021198; PubMed Central PMCID: PMC7593086.

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Tuyishime M, Garrido C, Jha S, Moeser M, Mielke D, LaBranche C, Montefiori D, Haynes BF, Joseph S, Margolis DM, Ferrari G. Improved killing of HIV-infected cells using three neutralizing and non-neutralizing antibodies. J Clin Invest. 2020 Oct 1;130(10):5157-5170. doi: 10.1172/JCI135557. PubMed PMID: 32584790; PubMed Central PMCID: PMC7524508.

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Moeser M, Nielsen JR, Joseph SB. Macrophage Tropism in Pathogenic HIV-1 and SIV Infections. Viruses. 2020 Sep 25;12(10). doi: 10.3390/v12101077. Review. PubMed PMID: 32992787; PubMed Central PMCID: PMC7601331.

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Margolis DM, Archin NM, Cohen MS, Eron JJ, Ferrari G, Garcia JV, Gay CL, Goonetilleke N, Joseph SB, Swanstrom R, Turner AW, Wahl A. Curing HIV: Seeking to Target and Clear Persistent Infection. Cell. 2020 Apr 2;181(1):189-206. doi: 10.1016/j.cell.2020.03.005. Epub 2020 Mar 26. Review. PubMed PMID: 32220311; PubMed Central PMCID: PMC7896558.

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James KS, Trumble I, Clohosey ML, Moeser M, Roan NR, Adimora AA, Joseph SB, Archin NM, Hudgens M, Soriano-Sarabia N. Measuring the contribution of γδ T cells to the persistent HIV reservoir. AIDS. 2020 Mar 1;34(3):363-371. doi: 10.1097/QAD.0000000000002434. PubMed PMID: 31764074; PubMed Central PMCID: PMC6994336.

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Joseph SB, Trunfio M, Kincer LP, Calcagno A, Price RW. What can characterization of cerebrospinal fluid escape populations teach us about viral reservoirs in the central nervous system?. AIDS. 2019 Dec 1;33 Suppl 2:S171-S179. doi: 10.1097/QAD.0000000000002253. Review. PubMed PMID: 31790378.

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Abrahams MR, Joseph SB, Garrett N, Tyers L, Moeser M, Archin N, Council OD, Matten D, Zhou S, Doolabh D, Anthony C, Goonetilleke N, Karim SA, Margolis DM, Pond SK, Williamson C, Swanstrom R. The replication-competent HIV-1 latent reservoir is primarily established near the time of therapy initiation. Sci Transl Med. 2019 Oct 9;11(513). doi: 10.1126/scitranslmed.aaw5589. PubMed PMID: 31597754; PubMed Central PMCID: PMC7233356.

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Goonetilleke N, Clutton G, Swanstrom R, Joseph SB. Blocking Formation of the Stable HIV Reservoir: A New Perspective for HIV-1 Cure. Front Immunol. 2019;10:1966. doi: 10.3389/fimmu.2019.01966. eCollection 2019. Review. PubMed PMID: 31507594; PubMed Central PMCID: PMC6714000.

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Srinivas N, Joseph SB, Robertson K, Kincer LP, Menezes P, Adamson L, Schauer AP, Blake KH, White N, Sykes C, Luciw P, Eron JJ, Forrest A, Price RW, Spudich S, Swanstrom R, Kashuba ADM. Predicting Efavirenz Concentrations in the Brain Tissue of HIV-Infected Individuals and Exploring their Relationship to Neurocognitive Impairment. Clin Transl Sci. 2019 May;12(3):302-311. doi: 10.1111/cts.12620. Epub 2019 Feb 27. PubMed PMID: 30675981; PubMed Central PMCID: PMC6510381.

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Bertero L, Joseph SB, Trunfio M, Allice T, Catera S, Imperiale D, Cassoni P, Kincer LP, Pirriatore V, Ghisetti V, Amasio E, Zanusso G, Bonora S, Di Perri G, Calcagno A. HIV-1 detection in the olfactory mucosa of HIV-1-infected participants. AIDS. 2019 Mar 15;33(4):665-674. doi: 10.1097/QAD.0000000000002102. PubMed PMID: 30608272.

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Pinzone MR, VanBelzen DJ, Weissman S, Bertuccio MP, Cannon L, Venanzi-Rullo E, Migueles S, Jones RB, Mota T, Joseph SB, Groen K, Pasternak AO, Hwang WT, Sherman B, Vourekas A, Nunnari G, O'Doherty U. Longitudinal HIV sequencing reveals reservoir expression leading to decay which is obscured by clonal expansion. Nat Commun. 2019 Feb 13;10(1):728. doi: 10.1038/s41467-019-08431-7. PubMed PMID: 30760706; PubMed Central PMCID: PMC6374386.

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Joseph SB, Swanstrom R. The evolution of HIV-1 entry phenotypes as a guide to changing target cells. J Leukoc Biol. 2018 Mar;103(3):421-431. doi: 10.1002/JLB.2RI0517-200R. Epub 2018 Feb 1. Review. PubMed PMID: 29389021.

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Trunfio M, Joseph SB, Ghisetti V, Romito A, Martini C, Cusato J, Audagnotto S, Pesci Kincer L, Ferrara M, Sala A, Imperiale D, Di Perri G, Calcagno A. Symptomatic cerebrospinal fluid HIV-1 escape with no resistance-associated mutations following low-level plasma viremia. J Neurovirol. 2018 Feb;24(1):132-136. doi: 10.1007/s13365-017-0605-1. Epub 2017 Dec 14. PubMed PMID: 29243133.

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Council OD, Joseph SB. Evolution of Host Target Cell Specificity During HIV-1 Infection. Curr HIV Res. 2018;16(1):13-20. doi: 10.2174/1570162X16666171222105721. Review. PubMed PMID: 29268687.

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Joseph J, Cinque P, Colosi D, Dravid A, Ene L, Fox H, Gabuzda D, Gisslen M, Beth Joseph S, Letendre S, Mukerji SS, Nath A, Perez-Valero I, Persaud D, Price RW, Rao VR, Sacktor N, Swanstrom R, Winston A, Wojna V, Wright E, Spudich S. Highlights of the Global HIV-1 CSF Escape Consortium Meeting, 9 June 2016, Bethesda, MD, USA. J Virus Erad. 2016 Oct 5;2(4):243-250. PubMed PMID: 27781109; PubMed Central PMCID: PMC5075354.

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Arrildt KT, LaBranche CC, Joseph SB, Dukhovlinova EN, Graham WD, Ping LH, Schnell G, Sturdevant CB, Kincer LP, Mallewa M, Heyderman RS, Rie AV, Cohen MS, Spudich S, Price RW, Montefiori DC, Swanstrom R. Phenotypic Correlates of HIV-1 Macrophage Tropism. J Virol. 2015 Nov;89(22):11294-311. doi: 10.1128/JVI.00946-15. Epub 2015 Sep 2. PubMed PMID: 26339058; PubMed Central PMCID: PMC4645658.

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Joseph SB, Swanstrom R, Kashuba AD, Cohen MS. Bottlenecks in HIV-1 transmission: insights from the study of founder viruses. Nat Rev Microbiol. 2015 Jul;13(7):414-25. doi: 10.1038/nrmicro3471. Epub 2015 Jun 8. Review. PubMed PMID: 26052661; PubMed Central PMCID: PMC4793885.

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Joseph SB, Arrildt KT, Sturdevant CB, Swanstrom R. HIV-1 target cells in the CNS. J Neurovirol. 2015 Jun;21(3):276-89. doi: 10.1007/s13365-014-0287-x. Epub 2014 Sep 19. Review. PubMed PMID: 25236812; PubMed Central PMCID: PMC4366351.

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Sturdevant CB, Joseph SB, Schnell G, Price RW, Swanstrom R, Spudich S. Compartmentalized replication of R5 T cell-tropic HIV-1 in the central nervous system early in the course of infection. PLoS Pathog. 2015 Mar;11(3):e1004720. doi: 10.1371/journal.ppat.1004720. eCollection 2015 Mar. PubMed PMID: 25811757; PubMed Central PMCID: PMC4374811.

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Joseph SB, Swanstrom R. HIV/AIDS. A fitness bottleneck in HIV-1 transmission. Science. 2014 Jul 11;345(6193):136-7. doi: 10.1126/science.1257425. PubMed PMID: 25013044.

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Joseph SB, Peck KM, Burch CL. Dominance effects of deleterious and beneficial mutations in a single gene of the RNA virus ϕ6. PLoS One. 2014;9(6):e97717. doi: 10.1371/journal.pone.0097717. eCollection 2014. PubMed PMID: 24945910; PubMed Central PMCID: PMC4063744.

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Price RW, Spudich SS, Peterson J, Joseph S, Fuchs D, Zetterberg H, Gisslén M, Swanstrom R. Evolving character of chronic central nervous system HIV infection. Semin Neurol. 2014 Feb;34(1):7-13. doi: 10.1055/s-0034-1372337. Epub 2014 Apr 8. Review. PubMed PMID: 24715483; PubMed Central PMCID: PMC4120280.

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Joseph SB, Arrildt KT, Swanstrom AE, Schnell G, Lee B, Hoxie JA, Swanstrom R. Quantification of entry phenotypes of macrophage-tropic HIV-1 across a wide range of CD4 densities. J Virol. 2014 Feb;88(4):1858-69. doi: 10.1128/JVI.02477-13. Epub 2013 Dec 4. PubMed PMID: 24307580; PubMed Central PMCID: PMC3911544.

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Gupta S, Gach JS, Becerra JC, Phan TB, Pudney J, Moldoveanu Z, Joseph SB, Landucci G, Supnet MJ, Ping LH, Corti D, Moldt B, Hel Z, Lanzavecchia A, Ruprecht RM, Burton DR, Mestecky J, Anderson DJ, Forthal DN. The Neonatal Fc receptor (FcRn) enhances human immunodeficiency virus type 1 (HIV-1) transcytosis across epithelial cells. PLoS Pathog. 2013;9(11):e1003776. doi: 10.1371/journal.ppat.1003776. Epub 2013 Nov 21. PubMed PMID: 24278022; PubMed Central PMCID: PMC3836734.

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Ping LH, Joseph SB, Anderson JA, Abrahams MR, Salazar-Gonzalez JF, Kincer LP, Treurnicht FK, Arney L, Ojeda S, Zhang M, Keys J, Potter EL, Chu H, Moore P, Salazar MG, Iyer S, Jabara C, Kirchherr J, Mapanje C, Ngandu N, Seoighe C, Hoffman I, Gao F, Tang Y, Labranche C, Lee B, Saville A, Vermeulen M, Fiscus S, Morris L, Karim SA, Haynes BF, Shaw GM, Korber BT, Hahn BH, Cohen MS, Montefiori D, Williamson C, Swanstrom R. Comparison of viral Env proteins from acute and chronic infections with subtype C human immunodeficiency virus type 1 identifies differences in glycosylation and CCR5 utilization and suggests a new strategy for immunogen design. J Virol. 2013 Jul;87(13):7218-33. doi: 10.1128/JVI.03577-12. Epub 2013 Apr 24. PubMed PMID: 23616655; PubMed Central PMCID: PMC3700278.

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Sturdevant CB, Dow A, Jabara CB, Joseph SB, Schnell G, Takamune N, Mallewa M, Heyderman RS, Van Rie A, Swanstrom R. Central nervous system compartmentalization of HIV-1 subtype C variants early and late in infection in young children. PLoS Pathog. 2012 Dec;8(12):e1003094. doi: 10.1371/journal.ppat.1003094. Epub 2012 Dec 27. PubMed PMID: 23300446; PubMed Central PMCID: PMC3531524.

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Arrildt KT, Joseph SB, Swanstrom R. The HIV-1 env protein: a coat of many colors. Curr HIV/AIDS Rep. 2012 Mar;9(1):52-63. doi: 10.1007/s11904-011-0107-3. Review. PubMed PMID: 22237899; PubMed Central PMCID: PMC3658113.

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Schnell G, Joseph S, Spudich S, Price RW, Swanstrom R. HIV-1 replication in the central nervous system occurs in two distinct cell types. PLoS Pathog. 2011 Oct;7(10):e1002286. doi: 10.1371/journal.ppat.1002286. Epub 2011 Oct 6. PubMed PMID: 22007152; PubMed Central PMCID: PMC3188520.

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Hall DW, Joseph SB. A high frequency of beneficial mutations across multiple fitness components in Saccharomyces cerevisiae. Genetics. 2010 Aug;185(4):1397-409. doi: 10.1534/genetics.110.118307. Epub 2010 Jun 1. PubMed PMID: 20516495; PubMed Central PMCID: PMC2927765.

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Joseph SB, Hanley KA, Chao L, Burch CL. Coinfection rates in Φ6 bacteriophage are enhanced by virus-induced changes in host cells. Evol Appl. 2009 Feb;2(1):24-31. doi: 10.1111/j.1752-4571.2008.00055.x. Epub 2008 Dec 23. PubMed PMID: 25567844; PubMed Central PMCID: PMC3352419.

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Hall DW, Mahmoudizad R, Hurd AW, Joseph SB. Spontaneous mutations in diploid Saccharomyces cerevisiae: another thousand cell generations. Genet Res (Camb). 2008 Jun;90(3):229-41. doi: 10.1017/S0016672308009324. PubMed PMID: 18593510.

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Joseph SB, Kirkpatrick M. Effects of the [PSI+] prion on rates of adaptation in yeast. J Evol Biol. 2008 May;21(3):773-80. doi: 10.1111/j.1420-9101.2008.01515.x. Epub 2008 Feb 29. PubMed PMID: 18312560.

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Joseph SB, Hall DW. Spontaneous mutations in diploid Saccharomyces cerevisiae: more beneficial than expected. Genetics. 2004 Dec;168(4):1817-25. doi: 10.1534/genetics.104.033761. PubMed PMID: 15611159; PubMed Central PMCID: PMC1448740.